ent-Cinacalcet Hydrochloride

Product Name ent-Cinacalcet Hydrochloride
Alternate Names Cinacalcet Impurities, Impurities of Cinacalcet
CAT No. CS-T-72472
CAS No. 1217809-88-5
Category Impurities
Stock Enquire
Mol. Wt. 393.87 g/mol
Mol. For. C₂₂H₂₃ClF₃N
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Cinacalcet
Smileys C[C@@H](C1=CC=CC2=C1C=CC=C2)NCCCC3=CC(C(F)(F)F)=CC=C3.Cl
Canonical Smiles CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
InchIKey QANQWUQOEJZMLL-NTISSMGPSA-N
Inchl InChI=1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m0./s1
IUPAC N-[(1S)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
Controlled No
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What is the usage and chemical information of ent-Cinacalcet Hydrochloride ?


Ent-Cinacalcet hydrochloride is a medication used for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. It is a calcimimetic agent that works by mimicking the action of calcium on the parathyroid gland, thereby reducing the production and secretion of parathyroid hormone (PTH). The chemical name for ent-Cinacalcet hydrochloride is (1R,3S)-1-(Naphthalen-1-yl)ethyl-3-(3-(trifluoromethyl)phenyl)imidazol-2-ylidene)amine hydrochloride. It is a white to off-white crystalline powder that is soluble in water and ethanol. The recommended dosage of ent-Cinacalcet hydrochloride is generally based on the patient's serum calcium levels and PTH levels. It is usually taken orally once a day with food. The medication should be taken at the same time each day to maintain consistent levels in the bloodstream. As with any medication, ent-Cinacalcet hydrochloride can cause side effects, including nausea, vomiting, diarrhea, and headache. It may also cause low blood calcium levels, which can lead to muscle cramps, tingling in the fingers and toes, and seizures. Overall, ent-Cinacalcet hydrochloride is a useful medication for managing secondary hyperparathyroidism in patients with chronic kidney disease. It is important to follow the prescribed dosage and to discuss any concerns or side effects with a healthcare provider.

Related Compounds

N-nitroso rac Cinacalcet | Cinacalcet Imine impurity | Dehydro Cinacalcet | Cinacalcet EP Impurity B | Cinacalcet Impurity 52 | Cinacalcetpropanamide IMPURITY | S-Cinacalcet | Cinacalcet 5,6-Dihydro Racemate Hydrochloride | N-formyl cinacalcet | Cinacalcet Impurity II | Cinacalcet Impurity A | Cinacalcet Impurity E HCl salt | N-Nitroso Cinacalcet Impurity C | Cinacalcet Impurity 51 | Cinacalcet Impurity 56 | Hexahydrophenyl Cinacalcet | Cinacalcet S-Isomer Hydrochloride | Tetrahydro Cinacalcet Hydrochloride | Cinacalcet Impurity 23 | Cinacalcet Hydroxy Impurity | Dihydro Cinacalcet Glucuronide | Cinacalcet Impurity B-HCl | Cinacalcet Impurity IV | Cinacalcet Impurity 17 | Cinacalcet Impurity 7 | Cinacalcet Dihydro Impurity 2 | Cinacalcet Impurity C | N-Nitroso-CINACALCET | Cinacalcet ortho-Trifluoromethyl Analog | Cinacalcet Impurity F | Cinacalcet Impurity 37 | Cinacalcet Impurity 18 | Cinacalcet para-Trifluoromethyl Analog | Cinacalcet Mesylate Analog | methyl 3-(3-(trifluoromethyl)cyclohexyl)propionate | Cinacalcet Impurity D | Cinacalcet Impurity 38 | Cinacalcet Regio Isomer | Cinacalcet Impurity I | Cinacalcet USP Related Compound B HCl salt | Cinacalcet Impurity E | Cinacalcet Impurity III | Cinacalcet Dihydro Impurity 1 HCl |

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