ent-Cinacalcet Hydrochloride

Product Name ent-Cinacalcet Hydrochloride
Alternate Names Cinacalcet Impurities, Impurities of Cinacalcet
CAT No. CS-T-72472
CAS No. 1217809-88-5
Category Impurities
Stock In stock
Mol. Wt. 393.87 g/mol
Mol. For. C₂₂H₂₃ClF₃N
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Cinacalcet
Smileys C[C@@H](C1=CC=CC2=C1C=CC=C2)NCCCC3=CC(C(F)(F)F)=CC=C3.Cl
Canonical Smiles CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
InchIKey QANQWUQOEJZMLL-NTISSMGPSA-N
Inchl InChI=1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m0./s1
IUPAC N-[(1S)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
Controlled No
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What is the usage and chemical information of ent-Cinacalcet Hydrochloride ?


Ent-Cinacalcet hydrochloride is a medication used for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. It is a calcimimetic agent that works by mimicking the action of calcium on the parathyroid gland, thereby reducing the production and secretion of parathyroid hormone (PTH). The chemical name for ent-Cinacalcet hydrochloride is (1R,3S)-1-(Naphthalen-1-yl)ethyl-3-(3-(trifluoromethyl)phenyl)imidazol-2-ylidene)amine hydrochloride. It is a white to off-white crystalline powder that is soluble in water and ethanol. The recommended dosage of ent-Cinacalcet hydrochloride is generally based on the patient's serum calcium levels and PTH levels. It is usually taken orally once a day with food. The medication should be taken at the same time each day to maintain consistent levels in the bloodstream. As with any medication, ent-Cinacalcet hydrochloride can cause side effects, including nausea, vomiting, diarrhea, and headache. It may also cause low blood calcium levels, which can lead to muscle cramps, tingling in the fingers and toes, and seizures. Overall, ent-Cinacalcet hydrochloride is a useful medication for managing secondary hyperparathyroidism in patients with chronic kidney disease. It is important to follow the prescribed dosage and to discuss any concerns or side effects with a healthcare provider.

Related Compounds

Cinacalcet Hydroxy Impurity | N-Nitroso-CINACALCET | Cinacalcet ortho-Trifluoromethyl Analog | Cinacalcet EP Impurity B | Cinacalcet Impurity 38 | Cinacalcet Impurity II | Cinacalcet Impurity E | methyl 3-(3-(trifluoromethyl)cyclohexyl)propionate | Cinacalcet Impurity D | Cinacalcet USP Related Compound B HCl salt | Cinacalcet Impurity IV | Cinacalcet Impurity 52 | S-Cinacalcet | Cinacalcet para-Trifluoromethyl Analog | Cinacalcet Dihydro Impurity 2 | Cinacalcet Impurity 56 | Cinacalcet Impurity 51 | Cinacalcet Regio Isomer | Cinacalcetpropanamide IMPURITY | Cinacalcet Impurity C | Cinacalcet Mesylate Analog | Cinacalcet Impurity I | Cinacalcet Impurity 23 | Cinacalcet Impurity III | Cinacalcet Impurity A | Tetrahydro Cinacalcet Hydrochloride | Cinacalcet Dihydro Impurity 1 HCl | Dihydro Cinacalcet Glucuronide | Cinacalcet 5,6-Dihydro Racemate Hydrochloride | Dehydro Cinacalcet | Cinacalcet Impurity 37 | Cinacalcet Impurity B-HCl | N-nitroso rac Cinacalcet | N-Nitroso Cinacalcet Impurity C | Hexahydrophenyl Cinacalcet | N-formyl cinacalcet | Cinacalcet Impurity 18 | Cinacalcet Impurity 17 | Cinacalcet Imine impurity | Cinacalcet Impurity 7 | Cinacalcet Impurity F | Cinacalcet Impurity E HCl salt |

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