Erythromycin-N-Oxide

Product Name Erythromycin-N-Oxide
Alternate Names Erythromycin Impurities, Impurities of Erythromycin
CAT No. CS-CM-00085
CAS No. 992-65-4
Category Impurities
Stock IN-Stock
Mol. Wt. 749.92 g/mol
Mol. For. C₃₇H₆₇NO₁₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Erythromycin
Purity 95%
Therapeutic Antihistamine
Smileys CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)[N+](C)(C)[O-])O)(C)O)C)C)O)(C)O
Canonical Smiles CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)[N+](C)(C)[O-])O)(C)O)C)C)O)(C)O
InchIKey LUIPOVCSQJTWHA-FXYCZVHTSA-N
Inchl InChI=1S/C37H67NO14/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(52-34-28(40)24(38(11,12)46)15-19(3)48-34)21(5)29(22(6)33(43)50-25)51-26-17-36(9,47-13)31(42)23(7)49-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26-,28-,29+,30-,31+,32-,34+,35-,36-,37+/m1/s1
IUPAC (2S,3R,4S,6R)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-3-hydroxy-N,N,6-trimethyloxan-4-amine oxide
Controlled No
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Erythromycin-N-Oxide is a derivative of erythromycin, a macrolide antibiotic that is commonly used to treat bacterial infections. Erythromycin-N-Oxide is created by the oxidation of erythromycin, resulting in the addition of an oxygen atom to the molecule. Erythromycin-N-Oxide has been found to have similar antibacterial properties to erythromycin, and is particularly effective against gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aureus. It is also effective against some gram-negative bacteria, including Haemophilus influenzae. The chemical structure of erythromycin-N-oxide allows it to penetrate bacterial cell walls, where it binds to the ribosome and prevents the production of proteins necessary for bacterial growth and replication. This ultimately leads to the death of the bacteria. Erythromycin-N-Oxide is commonly used in the treatment of respiratory tract infections, skin and soft tissue infections, and some sexually transmitted infections. It is available in oral and topical formulations. As with all antibiotics, it is important to use erythromycin-N-Oxide only as prescribed by a healthcare professional, and to complete the full course of treatment to ensure that all bacteria are eliminated. Overuse or misuse of antibiotics can lead to antibiotic resistance, which is a growing global health concern.

Related Compounds

N-demethyl-N-formyl-6-O-methyl-erythromycin A-9-oxime | Erythromycin EP Impurity E N-Oxide | Erythromycin A Enol Ether | Erythromycin Oxime | Erythromycin EP Impurity M | seco Erythromycin | Erythromycin propionate | Pseudo Erythromycin A Enol Ether | Erythromycin Impurity D | Erythromycin Ethylsuccinate EP Impurity G | Erythromycin A 6,9-Imino Ether | Erythromycin Impurity M | Silylated Erythromycin Oxime Ketal | Erythromycin EP Impurity A | Erythromycin Impurity 12 | Pseudoerythromycin A Hemiketal | N-Demethyl-N-Propanoyl Erythromycin | Erythromycin Ethylsuccinate | Azaerythromycin A 11,12-hydrogen borate | Erythromycin Impurity E | Erythromycin Ethyl Fumarate | Erythromycin lactobioate B | Erythromycin oxime base E-isomer | Erythromycin Impurity M | Erythromycin EP Impurity N | Erythromycin phthalyl ester | Erythromycin EP Impurity K | Erythromycin Impurity H | Erythromycin C |

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