Febuxostat Impurity 6

Product Name Febuxostat Impurity 6
Alternate Names Febuxostat Impurities, Impurities of Febuxostat
CAT No. CS-P-02568
CAS No. 1271738-74-9
Category Impurities
Stock IN-Stock
Mol. Wt. 362.44 g/mol
Mol. For. C₁₈H₂₂N₂O₄S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Febuxostat
Canonical Smiles CCOC(=O)C1=C(N=C(S1)C2=CC(=C(C=C2)OCC(C)C)C=NO)C
InchIKey XISYIGZAZNITQC-DJKKODMXSA-N
Inchl InChI=1S/C18H22N2O4S/c1-5-23-18(21)16-12(4)20-17(25-16)13-6-7-15(24-10-11(2)3)14(8-13)9-19-22/h6-9,11,22H,5,10H2,1-4H3/b19-9+
IUPAC ethyl 2-[3-[(E)-hydroxyiminomethyl]-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylate
Controlled No
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Febuxostat Impurity 6, also known as 2-aminopyrazine-3-carboxylic acid, is a synthetic organic compound that is used as a reference standard and an analytical tool in the quality control and development of febuxostat, a medication used in the treatment of hyperuricemia associated with gout. Febuxostat Impurity 6 is a purine analogue that inhibits the enzyme xanthine oxidase, which plays a crucial role in the production of uric acid in the body. By inhibiting this enzyme, febuxostat and its impurities like Impurity 6, reduce the levels of uric acid in the blood, thereby preventing gout attacks. Febuxostat Impurity 6 is a white to off-white crystalline powder that is soluble in water and organic solvents. Its chemical formula is C6H6N2O2 and its molecular weight is 138.13 g/mol. It can be synthesized by reacting 2-aminopyrazine with ethyl chloroformate, followed by hydrolysis with sodium hydroxide. In conclusion, Febuxostat Impurity 6 is an important reference standard that is used in the pharmaceutical industry for the quality control and development of febuxostat. Its chemical properties and inhibitory effects on xanthine oxidase make it an essential analytical tool in the research and development of new drugs for the treatment of gout and hyperuricemia.

Related Compounds

Febuxostat Impurity 5 | Febuxostat Isopropyl Ester | Febuxostat Impurity 12 | Desisobutyl Formyl Febuxostat | Febuxostat Impurity 30 | O-Desisobutyl O-n-Butyl Febuxostat ethyl ester | Febuxostat Butyl Ester Impurity | Ethyl 2-(3-formyl-2-hydroxyphenyl)-4-methylthiazole-5-carboxylate | Descyano Hydroxy Febuxostat | Febuxostat Impurity 16 | Febuxostat Impurity 21 | Febuxostat 67M-4 | Febuxostat Impurity 20 | Febuxostat ISOMER 2 | Hydroxy Febuxostat | Febuxostat Impurity 2 | Febuxostat Impurity 10 | Febuxostat Impurity C | Febuxostat Isobutyl Ester Impurity | O-Desisobutyl O-propyl Febuxostat | Febuxostat t-Butyl Ether Acid Impurity | Febuxostat Impurity 19 | Bromo Febuxostat | O-Desisobutyl O-n-Butyl Febuxostat | Febuxostat n-propyl ester imp | Febuxostat ISOMER 3 | Febuxostat 2-Butyl Isomer Ethyl Ester | Febuxostat Impurity 8 | Febuxostat Impurity 23 | Febuxostat Methyl Ester | Febuxostat Impurity 13 | Febuxostat Impurity 14 | Febuxostat Impurity 15 | Febuxostat Impurity 18 | Febuxostat Impurity 39 | Ethyl 2,2-dichloro-3-oxobutanoate | Febuxostat 2-butanol isomer | Febuxostat Impurity 22 | Febuxostat Isopropyl isomer | FEBUXOSTAT DEE IMPURITY |

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