Fexofenadine N-Oxide
| Product Name | Fexofenadine N-Oxide |
|---|---|
| Alternate Names | Fexofenadine Impurities, Impurities of Fexofenadine |
| CAT No. | CS-T-94016 |
| CAS No. | 1422515-52-3 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 517.66 g/mol |
| Mol. For. | C₃₂H₃₉NO₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Fexofenadine |
| Canonical Smiles | CC(C)(C1=CC=C(C=C1)C(CCC[N+]2(CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)[O-])O)C(=O)O |
| InchIKey | NZZCEGUGWNGQJN-UHFFFAOYSA-N |
| Inchl | InChI=1S/C32H39NO5/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33(38)22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36) |
| IUPAC | 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]-1-oxidopiperidin-1-ium-1-yl]butyl]phenyl]-2-methylpropanoic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Fexofenadine N-Oxide is a metabolite of fexofenadine, an antihistamine medication used to treat allergy symptoms such as runny nose, sneezing, itching, and watery eyes. Fexofenadine N-Oxide is also an antihistamine, but it has a different chemical structure and pharmacological properties compared to fexofenadine.
Fexofenadine N-Oxide is not commercially available as a medication, but it is used as a reference standard in drug testing and research studies. Its chemical formula is C32H39NO5, and its molecular weight is 521.66 g/mol. It is a white crystalline powder that is soluble in organic solvents such as methanol and ethanol.
The mechanism of action of fexofenadine N-Oxide is similar to that of fexofenadine. It blocks the H1 histamine receptor, which is responsible for allergic reactions. By blocking the receptor, fexofenadine N-Oxide reduces the symptoms of allergies. However, it has a lower affinity for the H1 receptor compared to fexofenadine, which means it is less potent.
Fexofenadine N-Oxide is rapidly metabolized in the liver and excreted in the urine. It has a half-life of approximately 14 hours, which means it stays in the body for a longer time compared to fexofenadine. However, its clinical significance is not well-established, and more research is needed to determine its therapeutic potential.
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Related Compounds
Fexofenadine Hydrochloride EP Impurity G | Fexofenadine Related Compound C | Fexofenadine HCl Impurity L | Fexofenadine Related Compound B | Fexofenadine Hydrochloride EP Impurity F | Fexofenadine hydrochloride USP Impurity A | Fexofenadine EP Impurity A | FEXOFENADINE EP IMPURITY A - HCl | Fexofenadine Hydrochloride EP Impurity D | Fexofenadine Impurity 37 | Fexofenadine Tertiary dehydrated Impurity | Fexofenadine P-Ethyl Ester | Fexafenadine EP Impurity B | meta-Fexofenadine Hydrochloride | Fexofenadine Hydrochloride EP Impurity C |