Florfenicol 13C6

[13C6]-Florfenicol is an isotopically labeled version of the antibiotic drug florfenicol. It is used primarily in research studies to track the fate and metabolism of the drug in various biological systems. The additional carbon-13 atoms in the labeled compound allow researchers to distinguish it from the unlabeled version of the drug, and to trace its movements and transformations through different tissues and organs. Florfenicol is a broad-spectrum antibiotic that belongs to the family of phenicol compounds. It works by inhibiting bacterial protein synthesis, and is effective against a wide range of Gram-negative and Gram-positive bacteria. It is commonly used in veterinary medicine to treat respiratory and enteric infections in livestock, as well as in aquaculture to control bacterial diseases in fish and shellfish. The addition of the six carbon-13 atoms to the structure of florfenicol does not alter its chemical properties or mode of action. However, it does make the labeled compound slightly heavier than the unlabeled version, which can affect its bioavailability and distribution in the body. Researchers must take this into account when designing experiments using [13C6]-florfenicol, and carefully monitor its concentration and movement in different tissues and fluids. Overall, [13C6]-florfenicol is a valuable tool for investigating the pharmacokinetics and pharmacodynamics of florfenicol and other related antibiotics, and for exploring the mechanisms of bacterial resistance and treatment.