Glibenclamide 13C6
| Product Name | Glibenclamide 13C6 |
|---|---|
| Alternate Names | Glibenclamide Stable Isotopes, Stable Isotopes of Glibenclamide |
| CAT No. | CS-EK-02835 |
| CAS No. | 10238-21-8 unlabeled |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Glibenclamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
[13C6]-Glibenclamide is a labeled form of the drug glibenclamide, which is commonly used to treat type 2 diabetes by stimulating insulin secretion from pancreatic beta cells. The labeled form contains six additional carbon-13 isotopes, which can be used for tracing metabolic pathways and understanding drug interactions in the body.
The chemical name of [13C6]-Glibenclamide is 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide-13C6. Its molecular formula is C23H23ClN4O5S and molecular weight is 533.02 g/mol.
The drug works by binding to the sulfonylurea receptor (SUR) on the beta cells, which leads to closure of ATP-sensitive potassium channels and subsequent depolarization of the cell membrane. This depolarization triggers calcium influx and insulin secretion. [13C6]-Glibenclamide can be used to study the binding affinity of the drug to the SUR and the downstream effects on insulin secretion.
Overall, [13C6]-Glibenclamide is a useful tool for understanding the pharmacokinetics and pharmacodynamics of glibenclamide in vivo. Its labeled carbon atoms can be detected using mass spectrometry, allowing for quantitative analysis of drug metabolism and distribution.
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Related Compounds
Glibenclamide EP Impurity A D3 |