Glimepiride (phenyl-​2,​3,​5,​6-​d4)

Product Name Glimepiride (phenyl-​2,​3,​5,​6-​d4)
Alternate Names Glimepiride Stable Isotopes, Stable Isotopes of Glimepiride
CAT No. CS-O-42117
CAS No. 1131981-32-2
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 494.64 g/mol
Mol. For. C24H30D4N4O5S
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Glimepiride
Controlled No
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Glimepiride is a medication that is used to treat type 2 diabetes mellitus. It belongs to a class of drugs known as sulfonylureas, which work by increasing insulin release from the pancreas, thereby lowering blood sugar levels. The drug is administered orally, typically once a day, with or without food. Glimepiride is metabolized in the liver and excreted in the urine. The chemical formula of Glimepiride is C24H34N4O5S, and its molecular weight is 490.63 g/mol. The compound contains a phenyl ring and a sulfonamide group, which are important for its biological activity. Glimepiride is available as tablets in various strengths, ranging from 1 mg to 4 mg. The deuterated form of Glimepiride, phenyl-2,3,5,6-d4 Glimepiride, is a labeled compound that is used for pharmacokinetic studies. It is synthesized by replacing the hydrogen atoms on the phenyl ring and the methyl group with deuterium. This modification does not affect the drug's efficacy or safety, but it allows researchers to track its movement in the body using mass spectrometry. Glimepiride is contraindicated in patients with type 1 diabetes, severe renal or hepatic impairment, or a history of hypersensitivity to sulfonylureas. It may cause hypoglycemia (low blood sugar), especially in elderly or malnourished patients. Common side effects include headache, dizziness, nausea, and skin rash. Patients should be advised to monitor their blood sugar levels regularly and to seek medical attention if they experience any symptoms of hypoglycemia.

Related Compounds

rac trans-Hydroxy Glimepiride-d5 | Glimepiride-d4 (phenylethyl-a,a,b,b-d4) | Glimepiride-d5 | Glimepiride D8 | trans-Carboxy Glimepiride-d5 |

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