L-Isoleucine-15N, N-Fmoc

L-Isoleucine-15N, N-Fmoc is a stable isotope-labeled derivative of L-isoleucine, a non-polar, aliphatic amino acid with a branched side chain. This compound is used in proteomics and peptide research applications, specifically in the synthesis of isotopically labeled peptides for use in mass spectrometry-based protein identification and quantification studies. L-Isoleucine-15N, N-Fmoc is a labeled version of L-isoleucine where the nitrogen atoms in the amino group of the molecule are replaced with the stable isotope 15N. The N-Fmoc (9-fluorenylmethoxycarbonyl) group is a common protecting group used in peptide synthesis to block the amino group and prevent unwanted reactions during the peptide elongation process. This compound is useful for the synthesis of isotopically labeled peptides because it allows for the differentiation of peptide fragments in mass spectrometry experiments, leading to more accurate protein identification and quantification. It can also be used in the synthesis of custom peptides for use in drug discovery and other research applications. In summary, L-Isoleucine-15N, N-Fmoc is a valuable tool for peptide synthesis and proteomics research. Its stable isotope labeling allows for accurate protein identification and quantification, making it an essential component in the field of mass spectrometry-based proteomics.