L-Valine-15N, N-Fmoc

L-Valine-15N, N-Fmoc is a chemical compound that is commonly used in peptide synthesis. It is a derivative of the amino acid L-Valine, which is an essential amino acid that cannot be synthesized by the human body and must be obtained through diet or supplementation. The addition of the Fmoc (fluorenylmethyloxycarbonyl) protecting group to the amino group of L-Valine-15N makes it a useful building block in peptide synthesis. Peptides are important biomolecules that play a crucial role in many physiological processes. They are composed of amino acids linked by peptide bonds, and can be synthesized using solid-phase peptide synthesis. L-Valine-15N, N-Fmoc is used as a starting material in the synthesis of peptides that contain the isotopic label 15N, which is often used in studies of protein structure and function. The Fmoc protecting group is removed from L-Valine-15N during the peptide synthesis process using a base such as piperidine, which exposes the amino group for further reaction. Once the peptide is synthesized, the Fmoc group can be removed using an acid such as trifluoroacetic acid to yield the final product. L-Valine-15N, N-Fmoc is a valuable tool for researchers studying protein structure and function, as well as for those working in the field of drug discovery. Its use in peptide synthesis allows for the production of peptides with specific isotopic labels, which can provide valuable information on the behavior of proteins in vivo.