Melphalan D8 Hydrochloride

Product Name Melphalan D8 Hydrochloride
Alternate Names Melphalan Stable Isotopes, Stable Isotopes of Melphalan
CAT No. CS-O-06754
CAS No. 1217854-43-7
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 349.71 g/mol
Mol. For. C₁₃H₁₁D₈Cl₃N₂O₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Melphalan
Therapeutic Anti-Cancer / Oncology
Smileys C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl.Cl
Canonical Smiles C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl.Cl
InchIKey OUUYBRCCFUEMLH-GTGANALVSA-N
Inchl InChI=1S/C13H18Cl2N2O2.ClH/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19;/h1-4,12H,5-9,16H2,(H,18,19);1H/t12-;/m0./s1/i5D2,6D2,7D2,8D2;
IUPAC (2S)-2-amino-3-[4-[bis(2-chloro-1,1,2,2-tetradeuterioethyl)amino]phenyl]propanoic acid;hydrochloride
Controlled No
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Melphalan D8 Hydrochloride is a deuterated version of Melphalan hydrochloride, a chemotherapy drug used to treat cancer. The deuterium isotope used in the preparation of Melphalan D8 Hydrochloride enables researchers to use it as an internal standard for mass spectrometry studies. The chemical structure of Melphalan D8 Hydrochloride is similar to that of Melphalan hydrochloride, with the substitution of deuterium at certain positions. Melphalan D8 Hydrochloride is typically administered intravenously or orally, and its usage is closely monitored by healthcare professionals due to its potential toxicity. It works by inhibiting the growth of cancer cells, especially those that divide rapidly. It is commonly used to treat multiple myeloma, ovarian cancer, and breast cancer, among other types of cancer. Melphalan D8 Hydrochloride is a highly reactive alkylating agent that forms covalent bonds with DNA, leading to the disruption of DNA replication and ultimately cell death. It also affects other cellular processes, such as protein synthesis and cell division. Melphalan D8 Hydrochloride has a half-life of approximately 1.5 hours and is primarily eliminated through the kidneys. As with all chemotherapy drugs, it can have side effects, including nausea, vomiting, hair loss, and a decreased ability to fight infections. However, its potential benefits in treating cancer often outweigh these risks.

Related Compounds

Melphalan D8 |

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