Metolazone D7

Product Name Metolazone D7
Alternate Names Metolazone Stable Isotopes, Stable Isotopes of Metolazone
CAT No. CS-O-06770
CAS No. 17560-51-9(Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 372.88 g/mol
Mol. For. C₁₆H₉D₇ClN₃O₃S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Metolazone
Purity Not less than 90 %
Smileys O=C1C2=CC([S](N)(=O)=O)=C(Cl)C=C2NC(C)N1C(C([2H])=C([2H])C([2H])=C3[2H])=C3C([2H])([2H])[2H]
Canonical Smiles CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl
InchIKey AQCHWTWZEMGIFD-UHFFFAOYSA-N
Inchl InChI=1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)
IUPAC 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
Controlled No
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Metolazone D7 is a deuterated form of the diuretic drug Metolazone, which is primarily used to treat hypertension and edema (fluid retention) associated with congestive heart failure. Metolazone D7 is a selective inhibitor of the sodium-chloride co-transporter in the distal convoluted tubule of the kidney, which prevents reabsorption of sodium and chloride ions and promotes excretion of water and electrolytes. Chemically, Metolazone D7 is a thiazide-like diuretic, which means it works by inhibiting the reabsorption of sodium and chloride ions in the kidneys. It is classified as a sulfonamide, and its chemical formula is C16H8D7ClN2O3S. Metolazone D7 is available as a white to off-white crystalline powder, which is soluble in methanol and slightly soluble in water. The recommended dosage of Metolazone D7 depends on the patient's condition and response to treatment. It is usually taken orally once daily, with or without food. The drug is metabolized in the liver and excreted in the urine, with a half-life of approximately 14 hours. Like all drugs, Metolazone D7 may cause side effects, including dizziness, headache, nausea, vomiting, diarrhea, and electrolyte imbalances. It may interact with other medications, especially those that affect electrolyte levels, such as corticosteroids and diuretics. In conclusion, Metolazone D7 is a deuterated form of the diuretic drug Metolazone, which is used to treat hypertension and edema. Its chemical formula is C16H8D7ClN2O3S, and it works by inhibiting the reabsorption of sodium and chloride ions in the kidneys. The drug is available as a white to off-white crystalline powder and is taken orally once daily. It may cause side effects and interact with other medications.

Related Compounds

Desmethyl Metolazone-d5 |

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