Miltefosine d4
| Product Name | Miltefosine d4 |
|---|---|
| CAT No. | CS-O-32889 |
| CAS No. | 58066-85-6 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 411.59 g/mol |
| Mol. For. | C₂₁H₄₂D₄NO₄P |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Smileys | O=[P](OC([2H])([2H])C([2H])([2H])[N+](C)(C)C)([O-])OCCCCCCCCCCCCCCCC |
| Canonical Smiles | CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C |
| InchIKey | PQLXHQMOHUQAKB-UHFFFAOYSA-N |
| Inchl | InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3 |
| IUPAC | hexadecyl 2-(trimethylazaniumyl)ethyl phosphate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Miltefosine d4 is a deuterated form of miltefosine, an orally active alkylphosphocholine compound that was initially developed as an antineoplastic agent, but has since been repurposed as an antiprotozoal drug. Miltefosine d4 is a heavy isotope-labeled version of the drug, which is used in pharmacokinetic and metabolism studies.
Miltefosine d4 is used as a metabolic tracer in pharmacological research to determine the pharmacokinetics and pharmacodynamics of miltefosine in the body. It is also used to monitor the pharmacokinetics of miltefosine in patients with visceral leishmaniasis.
The chemical formula of miltefosine d4 is C21H40D4NO4P, and it has a molecular weight of 423.64 g/mol. The drug is a white to slightly yellowish powder that is soluble in water and methanol, and practically insoluble in dichloromethane and diethyl ether.
The mechanism of action of miltefosine d4 is not fully understood, but it is believed to work by interfering with the phospholipid metabolism of the parasite, leading to membrane damage and cell death. Miltefosine d4 has been shown to be effective against a wide range of protozoan parasites, including Leishmania, Plasmodium, and Trypanosoma cruzi.
In conclusion, miltefosine d4 is a useful tool for pharmacokinetic and metabolism studies of miltefosine, and it has potential for further research in the treatment of protozoan infections.
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