N-(Acetyl-d3)-5-aminosalicylic Acid

Product Name N-(Acetyl-d3)-5-aminosalicylic Acid
CAT No. CS-O-14666
CAS No. 93968-79-7
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 198.19 g/mol
Mol. For. C₉H₆D₃NO4
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Canonical Smiles CC(=O)NC1=CC(=C(C=C1)O)C(=O)O
InchIKey GEFDRROBUCULOD-FIBGUPNXSA-N
Inchl InChI=1S/C9H9NO4/c1-5(11)10-6-2-3-8(12)7(4-6)9(13)14/h2-4,12H,1H3,(H,10,11)(H,13,14)/i1D3
IUPAC 2-hydroxy-5-[(2,2,2-trideuterioacetyl)amino]benzoic acid
Controlled No
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N-(Acetyl-d3)-5-aminosalicylic Acid, also known as N-Acetyl-5-aminosalicylic acid-d3, is a stable labeled form of the drug 5-aminosalicylic acid (5-ASA). It is commonly used in pharmacological research to study the metabolism and pharmacokinetics of 5-ASA in vivo and in vitro. 5-ASA is a non-steroidal anti-inflammatory drug (NSAID) that is used to treat inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease. 5-ASA is an active metabolite of sulfasalazine, which is a prodrug that is metabolized to release 5-ASA in the colon. N-Acetyl-5-aminosalicylic acid-d3 is a stable isotope-labeled form of 5-ASA that allows for precise quantification of 5-ASA levels in biological samples. The chemical formula of N-Acetyl-5-aminosalicylic acid-d3 is C9H6D3NO4, and its molecular weight is 214.22 g/mol. It is a white to off-white powder that is soluble in water and ethanol. In summary, N-Acetyl-5-aminosalicylic acid-d3 is a useful tool for pharmacological research that enables accurate measurements of 5-ASA levels in biological samples. Its stable isotope labeling allows for precise quantification of 5-ASA metabolism and pharmacokinetics, which is important in the development of new treatments for IBD.

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