N-Denitroso-N’-nitroso Lomustine-d4
| Product Name | N-Denitroso-N’-nitroso Lomustine-d4 |
|---|---|
| CAT No. | CS-T-73631 |
| CAS No. | 1346603-97-1 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Smileys | O=C(NC([2H])([2H])C([2H])([2H])Cl)N(N=O)C1CCCCC1 |
| Canonical Smiles | C1CCC(CC1)N(C(=O)NCCCl)N=O |
| InchIKey | IGMMTYZWNUSEEU-KXGHAPEVSA-N |
| Inchl | InChI=1S/C9H16ClN3O2/c10-6-7-11-9(14)13(12-15)8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)/i6D2,7D2 |
| IUPAC | 3-(2-chloro-1,1,2,2-tetradeuterioethyl)-1-cyclohexyl-1-nitrosourea |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-Denitroso-N’-nitroso Lomustine-d4 is a deuterated derivative of N-Denitroso-N’-nitroso Lomustine, which is an antineoplastic agent used in chemotherapy. It is commonly used to treat brain tumors, lymphomas, and other types of cancer. The deuterated version is used for research purposes to help determine the pharmacokinetics and metabolism of the drug in the body.
The chemical formula of N-Denitroso-N’-nitroso Lomustine-d4 is C9H13D4ClN6O2. It is a yellow crystalline powder that is soluble in water and has a molecular weight of 279.7 g/mol. The deuterium substitution in this compound helps in the identification and quantification of the compound in biological samples using analytical techniques such as mass spectrometry.
The mechanism of action of N-Denitroso-N’-nitroso Lomustine-d4 involves the inhibition of DNA synthesis and the formation of cross-links between DNA strands, leading to cell death. The drug is administered orally and is metabolized in the liver. The metabolites are excreted in the urine and feces.
N-Denitroso-N’-nitroso Lomustine-d4 is a potent drug that has the potential to cause various side effects such as nausea, vomiting, hair loss, decreased appetite, and anemia. Patients undergoing chemotherapy with this drug require close monitoring by their healthcare provider to manage and minimize these side effects.
In conclusion, N-Denitroso-N’-nitroso Lomustine-d4 is a deuterated derivative of an antineoplastic agent used in chemotherapy. It is used for research purposes to help understand the pharmacokinetics and metabolism of the drug in the body.
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