N-Desmethyl Loperamide D3

Product Name N-Desmethyl Loperamide D3
Alternate Names Loperamide Stable Isotopes, Stable Isotopes of Loperamide
CAT No. CS-T-52228
CAS No. 1189488-17-2
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 466.03 g/mol
Mol. For. C₂₈H₂₈D₃ClN₂O₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Loperamide
Smileys CNC(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4
Canonical Smiles CNC(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4
InchIKey ZMOPTLXEYOVARP-FIBGUPNXSA-N
Inchl InChI=1S/C28H31ClN2O2/c1-30-26(32)28(23-8-4-2-5-9-23,24-10-6-3-7-11-24)18-21-31-19-16-27(33,17-20-31)22-12-14-25(29)15-13-22/h2-15,33H,16-21H2,1H3,(H,30,32)/i1D3
IUPAC 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenyl-N-(trideuteriomethyl)butanamide
Controlled No
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N-Desmethyl Loperamide D3 is a deuterated analog of N-desmethyl loperamide, a metabolite of the anti-diarrheal medication loperamide. This compound is commonly used in pharmacokinetic studies to determine the metabolic fate of loperamide in vivo. N-Desmethyl Loperamide D3 is a white to off-white powder with a molecular weight of 387.5 g/mol. It is soluble in organic solvents such as methanol and dimethyl sulfoxide (DMSO) but is insoluble in water. This compound has a melting point of 168-170°C and a boiling point of 567.1°C at 760 mmHg. The structure of N-Desmethyl Loperamide D3 includes deuterium atoms, which are stable isotopes of hydrogen. These isotopes have different chemical properties than hydrogen, which can be advantageous in certain applications. Deuterium labeling is commonly used in drug metabolism studies to help distinguish the parent compound from its metabolites. In conclusion, N-Desmethyl Loperamide D3 is a useful tool for researchers studying the pharmacokinetics and metabolism of loperamide. Its deuterium labeling provides a unique advantage in these studies, allowing for more precise analysis of drug metabolism.

Related Compounds

Loperamide-D6 | Loperamide D6 Hydrochloride |

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