N-Methyl-N-nitrosourethane

Also known as: - Nitrosamine Impurities or nitrosamine impurities of -
Product Name N-Methyl-N-nitrosourethane
Alternate Names - Impurities, Impurities of -
CAT No. CS-T-34546
CAS No. 615-53-2
Category Impurities
Stock IN-Stock
Mol. Wt. 132.12 g/mol
Mol. For. C₄H₈N₂O₃
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API -
Canonical Smiles CCOC(=O)N(C)N=O
InchIKey CAUBWLYZCDDYEF-UHFFFAOYSA-N
Inchl InChI=1S/C4H8N2O3/c1-3-9-4(7)6(2)5-8/h3H2,1-2H3
IUPAC ethyl N-methyl-N-nitrosocarbamate
Controlled No
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N-Methyl-N-nitrosourethane (MNU) is a potent mutagenic and carcinogenic compound that belongs to the nitrosourea class of chemicals. It is commonly used in laboratory experiments to induce genetic mutations in animal models, particularly rodents. MNU is a colorless and odorless liquid that is soluble in water, ethanol, and other organic solvents. It is highly reactive and can cause severe damage to DNA and other cellular components. MNU is commonly used in genetic research to create animal models of human diseases that involve genetic mutations, such as cancer, neurodegenerative disorders, and developmental disorders. It is also used in plant breeding to create new cultivars with desired traits. MNU works by alkylating DNA, which causes mutations in the genetic code. This can lead to the activation of oncogenes or the inactivation of tumor suppressor genes, which can ultimately result in the development of cancer. Due to its mutagenic and carcinogenic properties, MNU is classified as a hazardous substance and should be handled with caution. It is important to follow proper safety protocols when working with MNU, including wearing protective clothing and handling it in a fume hood. Additionally, proper disposal of MNU and any materials contaminated with it is essential to prevent environmental contamination and potential health hazards.

Related Compounds

Fluconazole Impurity 27 Chloride | Atracurium cis-trans isomer | methyl 2-(dimethylamino)-2-phenylbutanoate | N,S-(Dicarboxymethyl)cysteine | Sugammadex vinyl impurity | Lithium ((3-(methacryloyloxy)propyl)sulfonyl)((trifluoromethyl)sulfonyl)amide | Methoxy polyethylene glycol succinate N-hydroxy succinimide | Ulinastatin JP Reference standard (3700 units) | Polybutylene terephthalate Impurity 1 | methyl 3-(3,4-dimethoxyphenyl)-2-methyloxirane-2-carboxylate | N-nitroso-4- hydrazinobenzenesulfonamide | Resmetirom Impurity 1 | YD-19 | Aminodihexylquat Nitroso Impurity | Diethyl 2-(2-(4-chlorophenyl)allyl)-2-((2-oxo-1,2-dihydroquinolin-4-yl)methyl)malonate | Doxazosin Acetylpiperazinyl impurity | Chloromethylisothiazolinone-methylisothiazolinone Mixture | Dioctyl Carbonate | methyl (1S,2S,5R)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate | Estradiol impurities - 1 | Methyl 4-chloro-3-oxopentanoate | N-benzyl diclofenac | Di-isonocyl phthalate | N-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-5-methoxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine | Methyl 3-(4-methoxyphenyl)-2-methyloxirane-2-carboxylate | sodium (2-((1R,3S,4aS,4bS,10aS,10bR,11S,12aS)-10b-fluoro-1,11-dihydroxy-3,10a,12a-trimethyl-2,8-dioxo-1,2,3,4,4a,4b,5,6,8,10a,10b,11,12,12a-tetradecahydrochrysen-1-yl)ethyl)phosphonate | Dydrogesterone Impurity C | N-(4-(3-ethoxy-2-hydroxypropoxy)phenyl)-3-(methylthio)propanamide | Resmetirom Impurity 2 | N-propyl cyclooct-2-en-1-amine | Fluorouracil Impurity 11 | diethyl 2-(((3-chlorophenyl)(nitroso) amino)methylene)malonate | Nifuraldezone | Dimethylamine sulfate | N-(4-(3-ethoxy-2-hydroxypropoxy)phenyl)-3-hydroxypropanamide | Sorafenib Impurity 16 | N-(4-acetamidobenzoyl)-L-glutamic acid | iopamidol Impurity 4 | Ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1,2-dimethyl-1H-indole-3-carboxylate | Vonoprazan Impurity 15Impurity | Methyl 2-bromo-2-(4-chlorophenyl)acetate | N,S-Diacetylcysteamine | N-nitroso-N-phenethyl acetamide | ONT 993 | Ethyl (R)-3-(3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanamido)propanoate | N-(4,5-dichloro-2-nitrophenyl)-N-nitrosoacetamide | Ribociclib Impurity B | Samidorphan methanobenzofuron isoquinoline | Sacubitril Impurity 57 | Quetiapine EP Impurity P diHCl salt | Adrenalin Nitroso Impurity 1 | Trazodone Bispiperzine Analog | eCF506 | Enpp1-IN-3 | propane-1,2,3-triyl triethane sulfonate | Ethyl Lauroyl Arginate-d23 Hydrochloride | Polybutylene terephthalate Impurity 2 | methyl 2,4-dichloro-3-oxopentanoate | N-Nitroso Venetoclax intermediate( VNL6) | Diethoxyethane | Enzalutamide N-Ethyl Impurity | Maleic anhydride-styrene copolymer | cis-1-Phenyl-2-propionylcyclopropane | N-Nitroso-(S,S)-ethylenediamine-N,N'-disuccinic acid | Oxo(OtBu)-γ-Glu(α-OtBu)-AEEA-OH | Desfluoro Pibrenstavir Impurity | Ceftriaxone 3-ene Isomer Disodium Salt | RAMIPRIL IMPURITY K DIASTEREOMER II | Resmetirom Impurity 9 | N-(4-((4-oxocyclohexa-2,5-dien-1-ylidene)amino)phenyl)acetamide |

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