N-Nitrosocimetidine
Also known as: Cimetidine Nitrosamine Impurities or nitrosamine impurities of Cimetidine| Product Name | N-Nitrosocimetidine |
|---|---|
| Alternate Names | Cimetidine Impurities, Impurities of Cimetidine |
| CAT No. | CS-ED-01970 |
| CAS No. | 73785-40-7 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 281.34 g/mol |
| Mol. For. | C₁₀H₁₅N₇OS |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Cimetidine |
| Canonical Smiles | CC1=C(N=CN1)CSCCN=C(NC#N)N(C)N=O |
| InchIKey | LFTUYYPQNCJQGN-UHFFFAOYSA-N |
| Inchl | InChI=1S/C10H15N7OS/c1-8-9(15-7-14-8)5-19-4-3-12-10(13-6-11)17(2)16-18/h7H,3-5H2,1-2H3,(H,12,13)(H,14,15) |
| IUPAC | 3-cyano-1-methyl-2-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]-1-nitrosoguanidine |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-Nitrosocimetidine is a chemical compound that belongs to the class of nitrosamines. It is commonly used as a pharmaceutical ingredient in the treatment of peptic ulcers and other gastrointestinal disorders. N-Nitrosocimetidine is a yellow crystalline powder that is soluble in water and polar solvents. It is known to be highly reactive and unstable, and can easily decompose in the presence of light, heat or acidic conditions.
The chemical structure of N-Nitrosocimetidine contains a nitroso group attached to a cimetidine molecule through a nitrogen atom. The nitroso group is known to be highly carcinogenic and can cause DNA damage by reacting with nucleophiles in the body. N-Nitrosocimetidine has been classified as a Group 2B carcinogen by the International Agency for Research on Cancer (IARC) due to its potential to cause cancer in humans.
Despite its potential health risks, N-Nitrosocimetidine is still used as an active ingredient in some pharmaceutical products. Its usage is regulated by several international organizations, and strict guidelines are in place to limit the concentrations of N-Nitrosocimetidine in pharmaceuticals. Manufacturers of pharmaceuticals containing N-Nitrosocimetidine are required to adhere to these guidelines to ensure the safety and efficacy of their products.
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Related Compounds
Cimetidine EP Impurity F | Cimetidine EP Impurity D | Hydroxymethyl cimetidine | Cimetidine EP Impurity I | Cimetidine EP Impurity A (HCl) | Descyano Cimetidine Dihydrochloride Salt | Cimetidine Impurity 2 | Cimetidine EP Impurity G | Cimetidine EP Impurity B | Methylene Disulfide Cimetidine | Cimetidine Amide Dihydrochloride | Cimetidine EP Impurity A | Cimetidine EP Impurity I HCl | Cimetidine EP Impurity H | Cimetidine EP Impurity E | Cimetidine EP Impurity C | Cimetidine Impurity 1 | Cimetidine Impurity 2 | Cimetidine Impurity 3 | Cimetidine Impurity 1 | Cimetidine EP Impurity J |