N-tert-Butoxycarbonyl-L-serine Methyl Ester

N-tert-Butoxycarbonyl-L-serine Methyl Ester (Boc-L-Ser-OMe) is a chemical compound that belongs to the amino acid derivatives family. It is commonly used in peptide synthesis as a protecting group for the L-serine amino acid. The Boc group protects the amine group of the L-serine, allowing for selective deprotection and further modification of the peptide chain. Boc-L-Ser-OMe is also used in pharmaceutical research and development as a starting material for the synthesis of various peptides and peptidomimetics. In terms of chemical information, Boc-L-Ser-OMe is a white to off-white solid with a molecular formula of C11H21NO5. It has a molecular weight of 251.29 g/mol and a melting point range of 72-74°C. Boc-L-Ser-OMe is soluble in polar solvents such as methanol, ethanol, and dimethylformamide. While Boc-L-Ser-OMe is generally considered safe to handle, it should be used with caution as it can be harmful if ingested or inhaled. Proper personal protective equipment, such as gloves and a lab coat, should be worn when handling this compound. Additionally, Boc-L-Ser-OMe should be stored in a cool, dry place away from direct sunlight and incompatible materials. In conclusion, Boc-L-Ser-OMe is a useful chemical compound for peptide synthesis and pharmaceutical research. Its unique properties make it an essential tool for the development of new drugs and therapies.