Neostigmine methyl sulphate

Product Name Neostigmine methyl sulphate
Alternate Names Neostigmine Impurities, Impurities of Neostigmine
CAT No. CS-O-30696
CAS No. 51-60-5
Category Impurities
Stock IN-Stock
Mol. Wt. 334.39 g/mol
Mol. For. C₁₃H₂₂N₂O₆S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Neostigmine
Purity >98%
Smileys CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)[O-]
Canonical Smiles CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)[O-]
InchIKey OSZNNLWOYWAHSS-UHFFFAOYSA-M
Inchl InChI=1S/C12H19N2O2.CH4O4S/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;1-5-6(2,3)4/h6-9H,1-5H3;1H3,(H,2,3,4)/q+1;/p-1
IUPAC [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate
Controlled No
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Neostigmine methyl sulphate is a drug used to treat certain types of muscle weakness. It is commonly used to treat myasthenia gravis, a condition that causes muscle weakness, particularly in the eyes, face, throat, and limbs. It works by inhibiting the action of acetylcholinesterase, an enzyme that breaks down the neurotransmitter acetylcholine. By blocking its action, neostigmine allows acetylcholine to accumulate and stimulate muscle contractions. Neostigmine methyl sulphate is a quaternary ammonium compound that is soluble in water and alcohol. It is administered via injection or orally and is rapidly absorbed into the bloodstream. The drug has a short half-life of approximately 50 minutes and is quickly metabolized by the liver. While effective in treating myasthenia gravis, neostigmine methyl sulphate also has potential side effects. These include nausea, vomiting, diarrhea, abdominal cramps, sweating, and increased salivation. In rare cases, it may cause muscle cramps or twitching, difficulty breathing, or a drop in blood pressure. Overall, neostigmine methyl sulphate is a valuable drug in treating muscle weakness associated with myasthenia gravis. However, it should only be used under the guidance of a healthcare professional and with careful monitoring for potential side effects.

Related Compounds

Neostigmine Nitroso Impurity 1 | Neostigmine Impurity 13 Metilsulfate | Nor Neostigmine | Methyl dimethylcarbamate | Neostigmine Impurity 14 Metilsulfate | Neostigmine Dimer 2 | Neostigmine Dimer | Neostigmine impurity A |

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