Neratinib Impurity 2

Neratinib Impurity 2 is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard for the analysis of Neratinib, which is a drug used in the treatment of breast cancer. The chemical name of Neratinib Impurity 2 is 6-chloro-2-methylimidazo[1,2-a]pyridine-3-carbonitrile, and its molecular formula is C9H6ClN3. It is a white to off-white crystalline powder that is sparingly soluble in water and soluble in organic solvents such as methanol, ethanol, and dimethylsulfoxide. The usage of Neratinib Impurity 2 is mainly for analytical purposes, specifically for the quantification and determination of impurities in Neratinib samples. This compound is used as a reference standard in analytical methods such as high-performance liquid chromatography (HPLC), gas chromatography (GC), and mass spectrometry (MS). It helps to ensure the accuracy and reliability of the analytical results by providing a known reference point for the identification and quantification of impurities in Neratinib samples. In terms of chemical information, Neratinib Impurity 2 is a derivative of imidazo[1,2-a]pyridine, which is a class of heterocyclic compounds that are widely used in medicinal chemistry. It is classified as a nitrile, which is a functional group that contains a carbon triple bond to nitrogen. This compound is also a halogenated derivative, with a chlorine atom attached to one of the carbon atoms in the imidazo[1,2-a]pyridine ring.