Nintedanib Carboxylic Acid

Product Name Nintedanib Carboxylic Acid
Alternate Names Nintedanib Impurities, Impurities of Nintedanib
CAT No. CS-P-01888
CAS No. 894783-71-2
Category Impurities
Stock IN-Stock
Mol. Wt. 525.60 g/mol
Mol. For. C₃₀H₃₁N₅O₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Nintedanib
Smileys O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)O
Canonical Smiles CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)O)O
InchIKey SDJMWYVJAVLZEG-UHFFFAOYSA-N
Inchl InChI=1S/C30H31N5O4/c1-33-14-16-35(17-15-33)19-26(36)34(2)23-11-9-22(10-12-23)31-28(20-6-4-3-5-7-20)27-24-13-8-21(30(38)39)18-25(24)32-29(27)37/h3-13,18,32,37H,14-17,19H2,1-2H3,(H,38,39)
IUPAC 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylic acid
Controlled No
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Nintedanib Carboxylic Acid is a chemical compound used in the treatment of idiopathic pulmonary fibrosis, a chronic lung disease that causes scarring of the lungs. It is an inhibitor of multiple tyrosine kinases, including vascular endothelial growth factor receptors (VEGFRs), fibroblast growth factor receptors (FGFRs), and platelet-derived growth factor receptors (PDGFRs). Nintedanib Carboxylic Acid works by blocking the signals that stimulate the growth and proliferation of cells in the lungs, which can lead to the formation of scar tissue. This helps to slow the progression of the disease and improve lung function. The chemical formula of Nintedanib Carboxylic Acid is C31H33N5O4, and it has a molecular weight of 539.63 g/mol. It is a white to off-white crystalline powder that is soluble in organic solvents, such as methanol and dimethyl sulfoxide. Nintedanib Carboxylic Acid is typically administered orally in the form of capsules or tablets. The recommended dose is 150 mg twice daily, taken with food. It is important to follow the prescribed dosing regimen and to not miss any doses, as this can affect the effectiveness of the treatment. Overall, Nintedanib Carboxylic Acid is an important medication for the treatment of idiopathic pulmonary fibrosis, and its use has been shown to improve lung function and quality of life for patients with this condition.

Related Compounds

Nintedanib N,N,-Dimethyl Aniline Impurity | Nintedanib Impurity 26 | N-nitrosoacetamido-Nintedanib | Nintedanib N-Methyl Aniline Impurity | Nintedanib N-Acetyl Impurity | Nintedanib E-isomer (Intedanib E-isomer) | Nintedanib Impurity 54 | Nintedanib Impurity G | Nintedanib Mono N-oxide | Nintedanib Impurity A | Nintedanib Impurity 15 | Nintedanib Impurity 22 | Nintedanib Impurity 28 | N1,N4-Bis(4-nitrophenyl)-1,4-piperazinediacetamide | Nintedanib Impurity 8 | Nintedanib Impurity C | Nintedanib Methyl impurity | N-Propanoyl Nintedanib | Nintedanib Impurity B | Nintedanib DP8 | Nintedanib Impurity 2 | Nintedanib Impurity 4 | methyl (Z)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate | Nintedanib Nitroso Impurity 2 | Nintedanib N-desmethyl N-ethyl | Nintedanib Impurity D | Nintedanib E-Isomer | Nintedanib Impurity 1 | Nintedanib Impurity 7 | Nintedanib 4-Nitrophenyl 2-(4-Nitroso) | Nintedanib DP7 | Nintedanib esylate Impurity A | Nintedanib DP6 | Nintedanib Ethoxyenolindole | Nintedanib N, N-Dimethyl amine impurity | N-Desmethyl Nintedanib | Nintedanib Impurity 24 | Nintedanib Ethyl Ester | Nintedanib Impurity 9 | N-Acetyl Nintedanib | Nintedanib Impurity E | Nintedanib Impurity 5 | Nintedanib Impurity 43 | Nintedanib Impurity F | Nintedanib Impurity 53 | N-Nitroso Nintedanib | Nintedanib Impurity 3 | Nintedanib Impurity 25 | Nintedanib acetyl impurity | Nintedanib Impurity 33 | Nintedanib Piperazinyl-N4-oxide | Nintedanib Impurity H |

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