Norketamine 13C6

[13C6]-Norketamine is a stable isotope-labeled form of Norketamine, a pharmacologically active metabolite of Ketamine. Ketamine is a dissociative anesthetic drug that has been used in human and veterinary medicine for over 50 years. Norketamine is produced in the liver by the cytochrome P450 enzyme system and contributes to the overall anesthetic effects of Ketamine. [13C6]-Norketamine is primarily used as a research tool in pharmacokinetic and pharmacodynamic studies. The labeled carbon atoms in [13C6]-Norketamine allow for precise tracking and quantification of its metabolism and distribution within the body. This is particularly useful in studying the effects of different dosages and administration routes of Ketamine, as well as investigating its potential therapeutic uses in treating depression, anxiety, and chronic pain. In terms of chemical information, [13C6]-Norketamine has a molecular formula of C14H17N2O with a molecular weight of 227.3 g/mol. The labeled carbon atoms are located at the 2, 4, 5, and 6 positions of the phenyl ring, which distinguishes it from the naturally occurring Norketamine. It is a white to off-white powder that is soluble in water and organic solvents. Overall, [13C6]-Norketamine is a valuable tool for understanding the pharmacology and therapeutic potential of Ketamine and its metabolites. Its stable isotope labeling provides a powerful analytical tool for researchers in the fields of pharmacology, neuroscience, and medicine.