Obeticholic acid methyl ester

Product Name Obeticholic acid methyl ester
Alternate Names Obeticholic Acid Impurities, Impurities of Obeticholic Acid
CAT No. CS-O-33354
CAS No. 951694-73-8
Category Impurities
Stock IN-Stock
Mol. Wt. 434.65 g/mol
Mol. For. C27H46O4
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Obeticholic Acid
Smileys C[C@@]([C@]1([H])[C@@H](CC)[C@H]2O)(CC[C@@H](O)C1)[C@]3([H])[C@]2([H])[C@@](CC[C@]4([H])[C@H](C)CCC(OC)=O)([H])[C@]4(C)CC3
Canonical Smiles CCC1C2CC(CCC2(C3CCC4(C(C3C1O)CCC4C(C)CCC(=O)OC)C)C)O
InchIKey QSDDPPUHXXAVJK-ZHWSUUDBSA-N
Inchl InChI=1S/C27H46O4/c1-6-18-22-15-17(28)11-13-27(22,4)21-12-14-26(3)19(16(2)7-10-23(29)31-5)8-9-20(26)24(21)25(18)30/h16-22,24-25,28,30H,6-15H2,1-5H3/t16-,17-,18-,19-,20+,21+,22+,24+,25-,26-,27-/m1/s1
IUPAC methyl (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
Controlled No
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Obeticholic acid methyl ester, also known as OBM, is a derivative of obeticholic acid, a synthetic bile acid used in the treatment of liver diseases such as primary biliary cholangitis. OBM is a promising candidate for the treatment of liver diseases due to its ability to modify the expression of genes involved in liver metabolism and inflammation. OBM is a white crystalline powder with a molecular weight of 393.54 g/mol. Its chemical formula is C24H38O4. The compound is soluble in organic solvents like methanol, ethanol, and chloroform. OBM has been found to have a number of biological activities, including anti-inflammatory, antioxidative, and antiproliferative effects. These properties make it a potential therapeutic agent for the treatment of liver diseases, including non-alcoholic steatohepatitis and liver fibrosis. In preclinical studies, OBM has been shown to improve liver function and reduce inflammation and fibrosis in animal models of liver disease. The compound has also been found to have a good safety profile in animal studies, with no significant toxicity observed at therapeutic doses. Overall, OBM shows promise as a potential treatment for liver diseases, and further research is needed to evaluate its efficacy and safety in humans.

Related Compounds

Obeticholic Acid Impurity 5 | Obeticholic Acid Impurity 9 | Obeticholic Acid Impurity 3 | Obeticholic Acid Impurity 6 | Obeticholic Acid D5 | DL-Allantoin-5-13C,1-15N | Obeticholic Acid Impurity 12 | Obeticholic Acid Impurity 16 | Obeticholic Acid Impurity 10 | Obeticholic acid D6 | Obeticholic Acid Impurity 18 | Obeticholic Acid Impurity 22 | Obeticholic Acid Impurity 1 | Obeticholic Acid Hydroxy ester impurity | Obeticholic Acid Impurity 21 | Obeticholic Acid Impurity 14 | Obeticholic Acid Impurity 25 | Obeticholic Acid Impurity 4 | Obeticholic acid-[PEG]-n-Ester | Obeticholic Acid Impurity 15 | Obeticholic Acid Impurity 7 | Obeticholic Acid Impurity 11 | Glyco Obeticholic acid D7 | Obeticholic Acid Impurity 20 | Obeticholic Acid Impurity 19 | Obeticholic Acid Impurity 23 | Obeticholic Acid Impurity 13 | Obeticholic Acid Impurity 2 | Obeticholic Acid Keto ester impurity | Obeticholic acid D5 (Ethyl-1,2,2,2-d4) | Obeticholic Acid Impurity 8 |

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