Osimertinib-d6
| Product Name | Osimertinib-d6 |
|---|---|
| Alternate Names | Osimertinib Stable Isotopes, Stable Isotopes of Osimertinib |
| CAT No. | CS-P-05673 |
| CAS No. | 1638281-44-3 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Osimertinib |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CN1C=C(C2=NC(NC(C=C(NC(C=C)=O)C(N(C)CCN(C([2H])([2H])[2H])C([2H])([2H])[2H])=C3)=C3OC)=NC=C2)C4=CC=CC=C14 |
| Canonical Smiles | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC |
| InchIKey | DUYJMQONPNNFPI-XERRXZQWSA-N |
| Inchl | InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32)/i2D3,3D3 |
| IUPAC | N-[2-[2-[bis(trideuteriomethyl)amino]ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Osimertinib-d6 is a deuterated version of Osimertinib, which is an oral medication used to treat non-small cell lung cancer (NSCLC). This drug is designed to target and inhibit the activity of the epidermal growth factor receptor (EGFR) protein, which plays a key role in the growth and spread of cancer cells. By inhibiting EGFR, Osimertinib-d6 can slow down or stop the growth of cancer cells, which can help to improve the patient's overall health and survival.
Chemically, Osimertinib-d6 is a deuterated version of Osimertinib, which means that some of its hydrogen atoms have been replaced with deuterium atoms. This modification can help to improve the drug's stability, bioavailability, and pharmacokinetic properties. In addition, the deuterium substitution can also improve the drug's safety profile, as it can reduce the likelihood of toxic metabolite formation.
The recommended dose of Osimertinib-d6 is typically based on the patient's body weight, medical history, and other factors. It is usually taken once a day, with or without food. Patients should take the drug at the same time each day, and should not stop or change the dose without consulting their doctor. Common side effects of Osimertinib-d6 include diarrhea, nausea, vomiting, and skin rash. In rare cases, the drug can cause more serious side effects such as interstitial lung disease or liver toxicity. Patients should report any unusual symptoms to their doctor immediately.
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