Penciclovir D4

Product Name Penciclovir D4
Alternate Names Penciclovir Stable Isotopes, Stable Isotopes of Penciclovir
CAT No. CS-O-10927
CAS No. 1020719-72-5
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 257.28 g/mol
Mol. For. C₁₀H₁₁D₄N₅O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Penciclovir
Purity Not less than 90 %
Therapeutic Antiretroviral / Anti-HIV
Smileys OCC(CO)C([2H])([2H])C([2H])([2H])N1C(NC(N)=NC2=O)=C2N=C1
Canonical Smiles C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N
InchIKey JNTOCHDNEULJHD-LNLMKGTHSA-N
Inchl InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18)/i1D2,2D2
IUPAC 2-amino-9-[1,1,2,2-tetradeuterio-4-hydroxy-3-(hydroxymethyl)butyl]-1H-purin-6-one
Controlled No
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Penciclovir D4 is a deuterated analogue of penciclovir, a potent antiviral drug that is used to treat infections caused by herpes simplex virus (HSV) and varicella-zoster virus (VZV). Penciclovir D4 is a labeled compound that contains four deuterium atoms in place of four hydrogen atoms in the molecular structure. This labeling allows for the accurate measurement of the drug in biological samples using mass spectrometry. Penciclovir D4 is primarily used as an analytical standard in pharmacokinetic and bioavailability studies of penciclovir. It is also used in research studies to investigate the metabolism, distribution, and excretion of penciclovir in the body. Penciclovir D4 is administered orally or topically and is rapidly converted to penciclovir in the body. The mechanism of action of penciclovir is similar to that of acyclovir, another antiviral drug that is used to treat HSV and VZV infections. Penciclovir inhibits the replication of the virus by blocking the viral DNA polymerase enzyme, which is essential for viral replication. Penciclovir D4 has a similar chemical structure and pharmacological properties as penciclovir, but the deuterium labeling provides additional benefits in analytical studies. In summary, Penciclovir D4 is a useful analytical standard that is used to study the pharmacokinetics and bioavailability of penciclovir. It is a labeled compound that is structurally similar to penciclovir and has the same mechanism of action. Penciclovir D4 is a valuable tool in the development of new antiviral drugs and in understanding the metabolism and distribution of penciclovir in the body.

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