Propafenone-d7 (propyl-d7) hydrochloride

Product Name Propafenone-d7 (propyl-d7) hydrochloride
Alternate Names Propafenone Stable Isotopes, Stable Isotopes of Propafenone
CAT No. CS-O-06889
CAS No. 1219799-06-0
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 384.95 g/mol
Mol. For. C₂₁H₂₁D₇ClNO₃
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Propafenone
Purity 95%
Smileys OC(CNC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])COC(C=CC=C1)=C1C(CCC2=CC=CC=C2)=O.Cl
Canonical Smiles CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl
InchIKey XWIHRGFIPXWGEF-YYEJEILISA-N
Inchl InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H/i1D3,2D2,14D2;
IUPAC 1-[2-[3-(1,1,2,2,3,3,3-heptadeuteriopropylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one;hydrochloride
Controlled No
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Size Price Quantity
5 MG $  285.00
$ 300.00
10 MG $  475.00
$ 500.00

What is the usage and chemical information of Propafenone-d7 (propyl-d7) hydrochloride ?


Propafenone-d7 hydrochloride, also known as propyl-d7 hydrochloride, is a deuterated form of the antiarrhythmic drug propafenone. It is a selective blocker of cardiac sodium channels and also has beta-blocking properties. Propafenone-d7 hydrochloride is used in the treatment of various types of cardiac arrhythmias, including atrial fibrillation and ventricular tachycardia. Chemically, propafenone-d7 hydrochloride is a substituted arylalkylamine, containing a propyl group. The deuterium atoms in the propyl group are stable isotopes of hydrogen, which are used as tracers in pharmacokinetic studies. Propafenone-d7 hydrochloride is a white crystalline powder that is soluble in water and ethanol. The pharmacological effects of propafenone-d7 hydrochloride are similar to those of the non-deuterated propafenone. It works by blocking the fast sodium channels in the heart, which slows down the conduction of electrical impulses and helps to restore normal heart rhythm. It also has beta-blocking properties, which reduce the heart rate and the workload on the heart. Propafenone-d7 hydrochloride is administered orally and is rapidly absorbed from the gastrointestinal tract. It has a half-life of about 6-10 hours and is metabolized in the liver. The drug is excreted mainly in the urine, with a small amount being excreted in the feces. The deuterium-labeled propyl group in propafenone-d7 hydrochloride allows for accurate measurement of its pharmacokinetics, which is useful in drug development and clinical research.

Related Compounds

Propafenone Dimer Impurity D10 | Propafenone-d5 (phenyl-d5) hydrochloride | Depropylamino Hydroxy Propafenone D5 | N-nitroso-propafenone D7 | N-Nitroso Propafenone (2,2,3,3,3-Propyl-D5) | Propafenone-d7 (propyl-d7) | Propafenone-d5 (n-propyl-2,2,3,3,3-d5) Hydrochloride | Despropyl Propafenone-d6 Oxalate | Depropylamino Chloro Propafenone-d5 | Propafenone-d5 (propoxy-d5) hydrochloride | N-Depropyl Propafenone-d5 Oxalate Salt |

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