Regorafenib D3

Product Name Regorafenib D3
Alternate Names Regorafenib Stable Isotopes, Stable Isotopes of Regorafenib
CAT No. CS-O-10712
CAS No. 1255386-16-3
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 485.83 g/mol
Mol. For. C₂₁H₁₂D₃ClF₃N₄O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Regorafenib
Purity 98.17
Therapeutic Anti-Cancer / Oncology
Smileys CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
Canonical Smiles CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
InchIKey FNHKPVJBJVTLMP-FIBGUPNXSA-N
Inchl InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)/i1D3
IUPAC 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-(trideuteriomethyl)pyridine-2-carboxamide
Controlled No
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Regorafenib D3, also known as Stivarga, is a medication used to treat cancerous tumours in the colon and rectum. It is a kinase inhibitor, which means that it works by blocking certain enzymes that promote the growth and spread of cancer cells. Regorafenib D3 is the deuterium labelled analogue of Regorafenib, which is an FDA approved drug that is used to treat gastrointestinal stromal tumors and metastatic colorectal cancer. The chemical structure of Regorafenib D3 consists of 21 carbon atoms, 15 hydrogen atoms, and 3 oxygen atoms. It also contains 3 deuterium atoms, which are heavier isotopes of hydrogen. The molecular formula of Regorafenib D3 is C20H20ClF3N6O4D3. Regorafenib D3 is typically administered orally, in the form of tablets. The recommended dosage and duration of treatment may vary depending on the specific type and stage of cancer being treated, as well as the patient's overall health and medical history. Like all medications, Regorafenib D3 may cause side effects. Some common side effects include fatigue, nausea, diarrhea, loss of appetite, and high blood pressure. It is important to speak with a healthcare provider about any potential risks and benefits of taking this medication.

Related Compounds

Regorafenib 13CD3 N-Oxide | N-Demethyl Regorafenib D3 N-Oxide | Regorafenib 13CD3 N-Glucuronide | Regorafenib M4 metabolite 13C6 | Regorafenib N-oxide D3 |

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