Rifamycin O

Product Name Rifamycin O
Alternate Names Rifamycin Impurities, Impurities of Rifamycin
CAT No. CS-T-61153
CAS No. 14487-05-9
Category Impurities
Stock IN-Stock
Mol. Wt. 753.79 g/mol
Mol. For. C₃₉H₄₇NO₁₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Rifamycin
Canonical Smiles CC1C=CC=C(C(=O)NC2=CC3(C4=C(C2=O)C(=C(C5=C4C(=O)C(O5)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)OCC(=O)O3)C
InchIKey RAFHKEAPVIWLJC-KQOHHTLASA-N
Inchl InChI=1S/C39H47NO14/c1-17-11-10-12-18(2)37(48)40-24-15-39(51-16-26(42)53-39)29-27(33(24)46)32(45)22(6)35-28(29)36(47)38(8,54-35)50-14-13-25(49-9)19(3)34(52-23(7)41)21(5)31(44)20(4)30(17)43/h10-15,17,19-21,25,30-31,34,43-45H,16H2,1-9H3,(H,40,48)/b11-10+,14-13+,18-12-/t17-,19+,20+,21+,25-,30-,31+,34+,38-,39?/m0/s1
IUPAC [(7'S,9'E,11'S,12'R,13'S,14'R,15'R,16'R,17'S,18'S,19'E,21'Z)-2',15',17'-trihydroxy-11'-methoxy-3',7',12',14',16',18',22'-heptamethyl-4,6',23',29'-tetraoxospiro[1,3-dioxolane-2,27'-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25-heptaene]-13'-yl] acetate
Controlled No
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Rifamycin O is a broad-spectrum antibiotic that is used to treat bacterial infections. Its mechanism of action involves inhibiting bacterial RNA synthesis by binding to the beta subunit of bacterial RNA polymerase. This prevents the transcription of RNA and ultimately leads to bacterial cell death. Rifamycin O is commonly used to treat tuberculosis, leprosy, and other mycobacterial infections. It is also effective against certain gram-positive and gram-negative bacteria, including Staphylococcus aureus and Streptococcus pneumoniae. Chemically, Rifamycin O is a member of the rifamycin family of antibiotics. It is a complex molecule consisting of a naphthalene ring and a macrocyclic lactone ring. The lactone ring contains a unique ansa-bridge structure, which gives Rifamycin O its distinctive properties. Rifamycin O is generally well-tolerated, with minimal side effects. However, it may cause gastrointestinal disturbances such as nausea, vomiting, and diarrhea. It may also interact with other medications, particularly those that are metabolized by the liver. Overall, Rifamycin O is an important antibiotic that is widely used in the treatment of bacterial infections. Its unique mechanism of action and broad-spectrum activity make it a valuable tool in the fight against infectious diseases.

Related Compounds

Rifamycin sodium salt | Desacetyl Rifamycin SV | Rifamycin Oxazine | Rifamycin R | Desacetyl Rifamycin S |

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