Roflumilast N-oxide
| Product Name | Roflumilast N-oxide |
|---|---|
| Alternate Names | Roflumilast Impurities, Impurities of Roflumilast |
| CAT No. | CS-O-31151 |
| CAS No. | 292135-78-5 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 419.21 g/mol |
| Mol. For. | C₁₇H₁₄Cl₂F₂N₂O₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Roflumilast |
| Purity | 95% |
| Therapeutic | Anti-Asthma / COPD |
| Smileys | FC(F)OC1=C(C=C(C(NC(C(Cl)=C[N]2=O)=C(C=2)Cl)=O)C=C1)OCC3CC3 |
| Canonical Smiles | C1CC1COC2=C(C=CC(=C2)C(=O)N=C3C(=CN(C=C3Cl)O)Cl)OC(F)F |
| InchIKey | KHXXMSARUQULRI-UHFFFAOYSA-N |
| Inchl | InChI=1S/C17H14Cl2F2N2O4/c18-11-6-23(25)7-12(19)15(11)22-16(24)10-3-4-13(27-17(20)21)14(5-10)26-8-9-1-2-9/h3-7,9,17,25H,1-2,8H2 |
| IUPAC | 3-(cyclopropylmethoxy)-N-(3,5-dichloro-1-hydroxypyridin-4-ylidene)-4-(difluoromethoxy)benzamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Roflumilast N-oxide is a drug used in the treatment of chronic obstructive pulmonary disease (COPD). It is a derivative of Roflumilast, which is a selective inhibitor of the enzyme phosphodiesterase-4 (PDE4). PDE4 is an enzyme that is responsible for the breakdown of cyclic adenosine monophosphate (cAMP), which is an important messenger molecule involved in the regulation of various physiological processes in the body. By inhibiting PDE4, Roflumilast N-oxide increases the levels of cAMP in the body, leading to a reduction in inflammation and the relaxation of the smooth muscles of the airways, which improves breathing in patients with COPD.
Chemically, Roflumilast N-oxide is a white to off-white powder that is soluble in water and methanol. It has a molecular formula of C17H14N2O4S and a molecular weight of 346.37 g/mol. The drug is administered orally, usually in the form of tablets, and its effects can be observed within a few hours of administration. However, it is important to note that Roflumilast N-oxide is not a cure for COPD, but rather a treatment that can help manage the symptoms of the disease. Like all drugs, Roflumilast N-oxide has potential side effects, including nausea, diarrhea, headache, and insomnia, among others. Therefore, it is important to consult a healthcare professional before using the drug and to follow their instructions carefully.
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Related Compounds
Roflumilast Impurity 9 | deschloro bromo Roflumilast | Roflumilast Impurity 8 | Roflumilast Dimer | Roflumilast Impurity 7 | Roflumilast Impurity 4 | Roflumilast difluoromethoxybenzoate |