safinamide methyl ester

Safinamide methyl ester is a chemical compound that belongs to the class of monoamine oxidase (MAO)-B inhibitors. It is an active ingredient used in the treatment of Parkinson's disease. This medication works by inhibiting the MAO-B enzyme, which is responsible for the degradation of dopamine in the brain. By inhibiting this enzyme, safinamide methyl ester increases the level of dopamine in the brain, which helps to reduce the symptoms of Parkinson's disease, such as tremors, stiffness, and slow movement. Safinamide methyl ester is typically administered orally in the form of tablets or capsules. It is usually taken two times a day, with or without food. The dosage of safinamide methyl ester depends on the severity of the Parkinson's disease symptoms and other individual factors such as age, weight, and medical conditions. It is important to follow the dosage instructions provided by the healthcare provider to achieve the best results. In terms of chemical information, safinamide methyl ester has a molecular formula of C17H19ClFN3O2 and a molecular weight of 343.8 g/mol. It is a white to pale yellow crystalline powder that is soluble in water and ethanol. The chemical structure of safinamide methyl ester consists of a benzylamine moiety, a fluorophenyl group, and a carboxylate ester. This compound has a high affinity for the MAO-B enzyme and is selective in its inhibition of this enzyme. Safinamide methyl ester has a relatively short half-life of around 2 hours and is metabolized in the liver. It is excreted mainly in the urine and feces.