Selumetinib 13C2,2H4

[13C2,2H4]-Selumetinib is a chemical compound that is used in scientific research as a tracer molecule to study the pharmacokinetics and metabolism of Selumetinib. Selumetinib is a promising drug candidate that is being developed for the treatment of various types of cancer, including melanoma and non-small cell lung cancer. The tracer molecule [13C2,2H4]-Selumetinib is labeled with stable isotopes of carbon and hydrogen, which allows researchers to track its movement and metabolism in biological systems. This information can be used to better understand how Selumetinib is absorbed, distributed, metabolized, and eliminated in the body, which is important for optimizing its therapeutic efficacy and minimizing its potential side effects. In addition to its use as a tracer molecule, [13C2,2H4]-Selumetinib also has important chemical properties that contribute to its biological activity. It is a potent inhibitor of MEK1/2, which are enzymes that play a critical role in the MAPK signaling pathway that is dysregulated in many types of cancer. By inhibiting MEK1/2, Selumetinib can block the growth and proliferation of cancer cells and induce their apoptosis, or programmed cell death. Overall, [13C2,2H4]-Selumetinib is a valuable tool for researchers who are working to develop more effective and targeted therapies for cancer. Its unique chemical properties and ability to act as a tracer molecule make it an important asset in the fight against cancer.