Simvastatin D3 Lactone
| Product Name | Simvastatin D3 Lactone |
|---|---|
| Alternate Names | Simvastatin Stable Isotopes, Stable Isotopes of Simvastatin |
| CAT No. | CS-O-02676 |
| CAS No. | 1002347-61-6 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 421.58 g/mol |
| Mol. For. | C₂₅H₃₅D₃O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Simvastatin |
| Purity | 95% |
| Therapeutic | Anti-Diabetic |
| Smileys | O=C(C(C([2H])([2H])[2H])(C)CC)O[C@@H]1[C@@]([C@H]2CC[C@@H](OC3=O)C[C@H](C3)O)([H])C(C=C[C@@H]2C)=C[C@H](C)C1 |
| Canonical Smiles | CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C |
| InchIKey | RYMZZMVNJRMUDD-LONBHWHVSA-N |
| Inchl | InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1/i4D3/t15-,16-,18+,19+,20-,21-,23-,25? |
| IUPAC | [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methyl-2-(trideuteriomethyl)butanoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Simvastatin D3 Lactone is a deuterated analog of Simvastatin Lactone, which is a well-known statin drug used to lower cholesterol levels in the blood. Simvastatin D3 Lactone is a stable isotopic form of Simvastatin Lactone, which contains three deuterium atoms instead of hydrogen atoms.
The chemical structure of Simvastatin D3 Lactone is similar to Simvastatin Lactone, except for the presence of deuterium atoms. It inhibits the enzyme HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonate. Mevalonate is a precursor of cholesterol, and the inhibition of HMG-CoA reductase reduces the production of cholesterol.
Simvastatin D3 Lactone is used in research as a stable isotope-labeled internal standard for the quantification of Simvastatin Lactone in biological samples. It is also used in pharmacokinetic and metabolic studies of Simvastatin Lactone.
The pharmacological and toxicological properties of Simvastatin D3 Lactone are similar to those of Simvastatin Lactone. The deuterium substitution does not affect the pharmacodynamic properties of Simvastatin Lactone. However, the pharmacokinetic properties of Simvastatin D3 Lactone are different from Simvastatin Lactone due to the difference in molecular weight.
In summary, Simvastatin D3 Lactone is a useful tool in research for the quantification and metabolic studies of Simvastatin Lactone. Its chemical properties are similar to Simvastatin Lactone, but the deuterium substitution provides unique advantages in analytical and pharmacokinetic studies.
Get an Instant Quote
Related Compounds
Simvastatin 13C D3 | Simvastatin-D6 sodium salt | Simvastatin D6 Lactone | Simvastatin hydroxy acid D3 ammonium salt | Simvastatin D3 | Simvastatin acid D3 | Simvastatin hydroxyl acid D6 Sodium salt | Simvastatin hydroxy acid D6 ammonium salt | Simvastatin Acid D6 |