Teneligliptin D8
| Product Name | Teneligliptin D8 |
|---|---|
| Alternate Names | Teneligliptin Stable Isotopes, Stable Isotopes of Teneligliptin |
| CAT No. | CS-O-03670 |
| CAS No. | 1391012-95-5 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 434.63 g/mol |
| Mol. For. | C₂₂H₂₂D₈N₆OS |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Teneligliptin |
| Purity | Not less than 90 % |
| Therapeutic | Anti-Diabetic |
| Smileys | CC1=NN(C2=CC=CC=C2)C(N3C([2H])([2H])C([2H])([2H])N([C@H]4C[C@@H](C(N5CCSC5)=O)NC4)C([2H])([2H])C3([2H])[2H])=C1 |
| Canonical Smiles | CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5 |
| InchIKey | WGRQANOPCQRCME-POOPOPQESA-N |
| Inchl | InChI=1S/C22H30N6OS/c1-17-13-21(28(24-17)18-5-3-2-4-6-18)26-9-7-25(8-10-26)19-14-20(23-15-19)22(29)27-11-12-30-16-27/h2-6,13,19-20,23H,7-12,14-16H2,1H3/t19-,20-/m0/s1/i7D2,8D2,9D2,10D2 |
| IUPAC | [(2S,4S)-4-[2,2,3,3,5,5,6,6-octadeuterio-4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Teneligliptin D8 is a stable-labeled isotopic version of the antidiabetic drug Teneligliptin, which is used to treat type 2 diabetes. It is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4), which is responsible for breaking down incretin hormones that regulate glucose homeostasis. By inhibiting DPP-4, Teneligliptin D8 can increase the levels of these hormones, leading to increased insulin secretion and decreased glucagon secretion, which ultimately results in improved glycemic control.
Teneligliptin D8 is typically used in clinical research studies to investigate the pharmacokinetics, pharmacodynamics, and metabolism of Teneligliptin in vivo. It is also used as an internal standard for the quantification of Teneligliptin in biological matrices using analytical techniques such as liquid chromatography-mass spectrometry (LC-MS).
The chemical formula of Teneligliptin D8 is C22H26D8N5O2, and it has a molecular weight of 406.54 g/mol. Its chemical structure is similar to that of Teneligliptin, with eight deuterium atoms replacing eight hydrogen atoms in the molecule. Teneligliptin D8 is a white to off-white powder that is soluble in water, methanol, and dimethyl sulfoxide (DMSO).
In conclusion, Teneligliptin D8 is a useful tool for investigating the pharmacological properties of Teneligliptin and its metabolism in vivo. Its stable-labeled isotopic composition allows for accurate quantification of Teneligliptin in biological samples, making it an essential component of diabetes research.
Get an Instant Quote
Related Compounds
Teneligliptin-d5 | Teneligliptin-2,2,6,6-d4 |