Trandolapril D5
| Product Name | Trandolapril D5 |
|---|---|
| Alternate Names | Trandolapril Stable Isotopes, Stable Isotopes of Trandolapril |
| CAT No. | CS-O-31046 |
| CAS No. | 1356847-98-7 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 435.57 g/mol |
| Mol. For. | C₂₄H₂₉D₅N₂O₅ |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Trandolapril |
| Purity | 98.3 |
| Therapeutic | Anti-Hypertensives |
| Smileys | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCCC3CC2C(=O)O |
| Canonical Smiles | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCCC3CC2C(=O)O |
| InchIKey | VXFJYXUZANRPDJ-YFCLCGKXSA-N |
| Inchl | InChI=1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1/i4D,5D,6D,9D,10D |
| IUPAC | (2S,3aR,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-(2,3,4,5,6-pentadeuteriophenyl)butan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Trandolapril D5 is a deuterium-labeled analog of trandolapril, an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure.
Like trandolapril, trandolapril D5 works by inhibiting the activity of ACE, which is responsible for converting angiotensin I to angiotensin II. By blocking this conversion, trandolapril D5 reduces the production of angiotensin II, a potent vasoconstrictor, and thereby dilates blood vessels, promoting blood flow and reducing blood pressure.
Trandolapril D5 is typically administered orally, and its effects are dose-dependent, with higher doses producing greater reductions in blood pressure. It is metabolized in the liver and excreted in the urine, with a half-life of approximately 6 hours.
In terms of chemical information, trandolapril D5 has a molecular formula of C24H32D5N3O4, with a molecular weight of 453.63 g/mol. It is a white to off-white powder that is soluble in water and ethanol, and has a melting point of approximately 120-125°C.
Overall, trandolapril D5 is a valuable tool for researchers studying the pharmacokinetics and pharmacodynamics of trandolapril, and may have potential applications in drug development and clinical studies.
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Related Compounds
Trandolaprilat D6 | Trandolapril D6 | Trandolaprilat D5 |