Valsartan D9

Product Name Valsartan D9
Alternate Names Valsartan Stable Isotopes, Stable Isotopes of Valsartan
CAT No. CS-O-02862
CAS No. 1089736-73-1
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 444.57 g/mol
Mol. For. C₂₄H₂₀D₉N₅O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Valsartan
Purity 95%
Therapeutic Anti-Hypertensives
Smileys O=C(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])N([C@H](C(O)=O)C(C)C)CC1=CC=C(C2=C(C3=NN=NN3)C=CC=C2)C=C1
Canonical Smiles CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O
InchIKey ACWBQPMHZXGDFX-KDDXQTGLSA-N
Inchl InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1/i1D3,4D2,5D2,10D2
IUPAC (2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
Controlled No
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Valsartan D9 is a deuterated form of the angiotensin II receptor antagonist Valsartan. It is an antihypertensive medication that is used to treat high blood pressure, heart failure, and to reduce the risk of death after a heart attack. Valsartan D9 works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow and raises blood pressure. Chemically, Valsartan D9 is a white to off-white crystalline powder that is sparingly soluble in water. Its molecular formula is C24H24D9N5O3, and its molecular weight is 451.6 g/mol. The deuterium substitution in Valsartan D9 does not significantly affect its pharmacological properties but enhances the specificity of its analysis in biological samples by mass spectrometry. The recommended dosage of Valsartan D9 varies depending on the condition being treated and the patient's age, weight, and medical history. It is usually taken orally once or twice a day, with or without food. The medication is metabolized in the liver and excreted in the feces and urine, with a half-life of about 6 hours. Like other medications, Valsartan D9 may cause side effects such as dizziness, headache, diarrhea, fatigue, and cough. It may also interact with other drugs, including diuretics, potassium supplements, and nonsteroidal anti-inflammatory drugs (NSAIDs). In conclusion, Valsartan D9 is a useful medication for managing hypertension and heart failure. Its deuterated form allows for more accurate and sensitive analysis in biological samples. However, patients should be aware of its potential side effects and drug interactions and should consult their healthcare provider before taking this medication.

Related Compounds

Valsartan D3 | Valsartan D8 |

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