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- Synonyms:Dolutegravir O-β-D-Glucuronide
- Chemical Name:Dolutegravir O-β-D-Glucuronide
- Country of Origin:India
- Application Notes:Dolutegravir O-β-D-Glucuronide is a metabolite of Dolutegravir (D528800); a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
- Product Category:Dolutegravir Glucuronides
Dolutegravir O-β-D-Glucuronide is identified by CAS No. 1485692-21-4 and is chemically known as Dolutegravir O-β-D-Glucuronide.
Dolutegravir O-β-D-Glucuronide is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Dolutegravir.
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