Tert-Butanol-d10, also known as deuterated tert-butanol [(CH3)3CDO], is a deuterated form of tert-butanol, where all ten hydrogen atoms have been replaced with deuterium (a stable isotope of hydrogen). Deuterated compounds like tert-Butanol-d10 find various applications in chemistry, spectroscopy, and research due to their unique properties. Here are some common applications for tert-Butanol-d10:
1. NMR Spectroscopy: Deuterated solvents like tert-Butanol-d10 are frequently used as NMR (Nuclear Magnetic Resonance) solvents. They provide clear, well-defined NMR spectra, making it easier to analyze and characterize hydrogen-containing compounds in solution.
2. Spectroscopic Analysis: tert-Butanol-d10 can be used in various spectroscopic techniques, including IR (Infrared) and Raman spectroscopy, as a reference material or solvent. Its distinct spectral properties can aid in characterizing other compounds.
3. Chemical Reactions: Researchers may use tert-Butanol-d10 as a solvent or reagent in chemical reactions, particularly in studies where deuterium substitution can affect reaction pathways or mechanisms.
4. Kinetic Studies: Deuterium-labeled compounds like tert-Butanol-d10 are useful in kinetic studies to trace the progress of reactions over time, helping researchers understand reaction mechanisms and rates.
5. Hydrogen Exchange Studies: Deuterium exchange studies involve tracking the exchange of deuterium with protium (normal hydrogen) in molecules. tert-Butanol-d10 can be used in such studies to investigate the exchange kinetics of hydrogen atoms.
6. Pharmaceutical Research: It may find applications in pharmaceutical research, especially in the study of drug interactions and metabolism, where the deuterium label can be used to trace the fate of specific functional groups in drug molecules.
7. Organic Synthesis: tert-Butanol-d10 can be employed as a solvent, reactant, or reagent in organic synthesis, where deuterium substitution can have specific effects on the outcome of reactions.
8. Calibration Standards: It can serve as a calibration standard for analytical instruments, ensuring precise and consistent measurements, particularly in mass spectrometry and other analytical techniques.
9. Catalysis Studies: In some catalysis studies, deuterated compounds are used to investigate the mechanisms and pathways of catalytic reactions, as deuterium labeling can provide insights into hydrogen transfer processes.
10. Material Science: Researchers may use tert-Butanol-d10 in material science studies, particularly in the characterization of polymers and other materials.
The choice to use tert-Butanol-d10 or any deuterated compound depends on the specific requirements of the experiment or analysis and should be made with consideration of safety and regulatory guidelines.
PubChem
https://pubchem.ncbi.nlm.nih.gov/substance/313057429#section=Related-Records
tert-Butanol-d10
https://commonchemistry.cas.org/detail?cas_rn=53001-22-2
(2H10)-2-Methylpropan-2-ol
https://pubchem.ncbi.nlm.nih.gov/substance/?source=chemidplus&sourceid=0053001222
CompTox Chemicals Dashboard Chemical Lists
https://comptox.epa.gov/dashboard/chemical-lists/
(2H10)-2-methylpropan-2-ol
https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/88597
tert-Butanol-d10
https://spectrabase.com/spectrum/HuzZWhzsAPq
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