Product Name |
Loperamide-D6 |
Alternate Names |
Loperamide Stable Isotopes, Stable Isotopes of Loperamide |
CAT No. |
CS-O-02923
|
CAS No. |
1189574-93-3 |
Category |
Stable Isotopes |
Stock |
IN-Stock
|
Mol. Wt. |
483.07 g/mol |
Mol. For. |
C₂₉H₂₇D₆ClN₂O₂
|
Hazardous |
This is a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Loperamide |
Smileys |
O=C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])C(C1=CC=CC=C1)(C2=CC=CC=C2)CCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3 |
Controlled |
No |
Shipping |
Free for purchase above 1000$ |
Delivery |
In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
Return |
Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
Ordering |
Place your order online or by email sales@clearsynth.com |
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Loperamide is a medication used to treat diarrhea. It works by slowing down the movement of the intestines, which helps to reduce the frequency and urgency of bowel movements. Loperamide-D6 is a deuterated form of loperamide, which means that it contains six deuterium atoms in place of six hydrogen atoms. This modification is intended to improve the drug's pharmacokinetic properties by increasing its half-life and reducing its clearance rate.
The chemical formula of loperamide-D6 is C29H43D6N3O2. It has a molecular weight of 470.77 g/mol and a melting point of 223-226°C. Loperamide-D6 is a white to off-white crystalline powder that is slightly soluble in water and freely soluble in ethanol.
The recommended dosage of loperamide-D6 varies depending on the severity of the diarrhea and the age of the patient. It is typically taken orally as a tablet or capsule. Loperamide-D6 should not be used in patients with a known hypersensitivity to the drug or in those with abdominal pain, constipation, or inflammatory bowel disease. It should also be used with caution in patients with liver or kidney disease, as these organs are involved in the metabolism and elimination of the drug.
In conclusion, loperamide-D6 is a useful medication for the treatment of diarrhea. Its deuterated form may offer certain pharmacokinetic advantages over the non-deuterated form, although further research is needed to fully evaluate its safety and efficacy.