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Home Sofosbuvir Impurity CS-T-84999

Sofosbuvir 3’,5’-Bis-(S)-phosphate

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Sofosbuvir 3’,5’-Bis-(S)-phosphate

Impurity · API Family: Sofosbuvir · CAT No. CS-T-84999 · CAS No. 1337482-17-3
Added to RFQ
For Research & Analytical Purposes. Not for Personal use.
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Packaging & Handling

Indicative product packaging is shown for visual reference. Actual packaging may vary based on pack size, quantity, storage condition and shipping requirements.

Documentation Available
Detailed specifications, certificates, and supporting documents are available upon request.
Storage: Refer MSDS for complete information.
Hazard: Refer MSDS for accurate information.

Sofosbuvir 3’,5’-Bis-(S)-phosphate Product Information

Sofosbuvir 3’,5’-Bis-(S)-phosphate is listed under Impurity and is intended for analytical research, quality control and pharmaceutical reference standard applications. It is associated with Sofosbuvir. The product is supplied by Clearsynth under CAT No. CS-T-84999.

Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight and product enquiry details.

Technical Data

Product Name
Sofosbuvir 3’,5’-Bis-(S)-phosphate
CAS No.
1337482-17-3
CAT No.
CS-T-84999
HSN Code
38229010
Country of Origin
Can be shipped from India, Canada and USA
Molecular Formula
C34H45FN4O13P2
Molecular Weight
798.69
Category
API Family
Storage Condition
Refer MSDS for complete information.
Hazard Compound
Refer MSDS for accurate information.

Description

Regulatory Description
Sofosbuvir 3’,5’-Bis-(S)-phosphate is supplied with detailed characterization data compliant with regulatory guideline. Sofosbuvir 3’,5’-Bis-(S)-phosphate can be used for analytical method development, method validation (AMV), Quality Control (QC) application for Abbreviated New Drug Application (ANDA), or during commercial production of Sofosbuvir.
Overview
Sofosbuvir 3',5'-Bis-(S)-phosphate is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-ß-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Synonyms
Sofosbuvir 3’,5’-Bis-(S)-phosphate
Application Notes
Sofosbuvir 3',5'-Bis-(S)-phosphate is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-ß-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
References

Product Applications & Regulatory Search Terms

Useful product, supplier and regulatory search terms for this reference standard.

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