4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2
Added to RFQ
For Research & Analytical Purposes. Not for Personal use.
Packaging & Handling
Indicative product packaging is shown for visual reference. Actual packaging may vary based on pack size, quantity, storage condition and shipping requirements.
Documentation Available
Detailed specifications, certificates, and supporting documents are available upon request.
Detailed specifications, certificates, and supporting documents are available upon request.
Storage: Refer MSDS for complete information.
Hazard: Refer MSDS for complete information.
4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2 Product Information
4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2 is listed under Stable Isotopes and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-97655.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight and product enquiry details.
Technical Data
Product Name
4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2
CAT No.
CS-T-97655
HSN Code
38229010
Country of Origin
Can be shipped from India, Canada and USA
Molecular Formula
C2813CH25F7N215N2O3
Molecular Weight
613.5
Category
Storage Condition
Refer MSDS for complete information.
Hazard Compound
Refer MSDS for complete information.
Description
Regulatory Description
4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2 is supplied with detailed characterization data compliant with regulatory guideline. 4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2 can be used for analytical method development, method validation (AMV), Quality Control (QC), ANDA-related analytical work, and commercial pharmaceutical research applications.
Overview
"4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2 is the labeled analogue of 4-Defluoro-4-(p-fluorophenyl)aprepitant (D228722), an impurity of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic."
Synonyms
4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2
Application Notes
"4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2 is the labeled analogue of 4-Defluoro-4-(p-fluorophenyl)aprepitant (D228722), an impurity of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic."
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