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Home Fingolimod API CS-T-24885

Fingolimod hydrochloride

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Fingolimod hydrochloride

API · API Family: Fingolimod · CAT No. CS-T-24885 · CAS No. 162359-56-0
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Documentation Available
Detailed specifications, certificates, and supporting documents are available upon request.
Storage: Refer MSDS for complete information.
Hazard: Refer MSDS for accurate information.

Fingolimod hydrochloride Product Information

Fingolimod hydrochloride is listed under API and is intended for analytical research, quality control and pharmaceutical reference standard applications. It is associated with Fingolimod. The product is supplied by Clearsynth under CAT No. CS-T-24885.

Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight and product enquiry details.

Technical Data

Product Name
Fingolimod hydrochloride
CAS No.
162359-56-0
CAT No.
CS-T-24885
HSN Code
38229010
Country of Origin
Can be shipped from India, Canada and USA
Molecular Formula
C19H34ClNO2
Molecular Weight
343.93
Category
API Family
Storage Condition
Refer MSDS for complete information.
Hazard Compound
Refer MSDS for accurate information.

Description

Regulatory Description
Fingolimod hydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Fingolimod hydrochloride can be used for analytical method development, method validation (AMV), Quality Control (QC) application for Abbreviated New Drug Application (ANDA), or during commercial production of Fingolimod.
Overview
"FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively)."
Synonyms
Fingolimod hydrochloride
Application Notes
"FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively)."
References

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