N-Desmethyl ponatinib
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For Research & Analytical Purposes. Not for Personal use.
Packaging & Handling
Indicative product packaging is shown for visual reference. Actual packaging may vary based on pack size, quantity, storage condition and shipping requirements.
Documentation Available
Detailed specifications, certificates, and supporting documents are available upon request.
Detailed specifications, certificates, and supporting documents are available upon request.
Storage: Refer MSDS for complete information.
Hazard: Refer MSDS for complete information.
N-Desmethyl ponatinib Product Information
N-Desmethyl ponatinib is listed under Metabolite and is intended for analytical research, quality control and pharmaceutical reference standard applications. It is associated with Ponatinib. The product is supplied by Clearsynth under CAT No. CS-EK-02100.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight and product enquiry details.
Technical Data
Product Name
N-Desmethyl ponatinib
CAS No.
943319-87-7
CAT No.
CS-EK-02100
HSN Code
38229010
Country of Origin
Can be shipped from India, Canada and USA
Molecular Formula
C28H25F3N6O
Molecular Weight
518.53
Category
API Family
Storage Condition
Refer MSDS for complete information.
Hazard Compound
Refer MSDS for complete information.
Description
Regulatory Description
N-Desmethyl ponatinib is supplied with detailed characterization data compliant with regulatory guideline. N-Desmethyl ponatinib can be used for analytical method development, method validation (AMV), Quality Control (QC) application for Abbreviated New Drug Application (ANDA), or during commercial production of Ponatinib.
Overview
Ponatinib Active Metabolite AP24567(M42) is a research reagent applied in pharmaceuticals and cancer treatment. Ponatinib Active Metabolite AP24567(M42) is an analog of Ponatinib (P688250) which is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib (P688250) is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor It is a COVID19-related research product.
Synonyms
N-Desmethyl ponatinib
Application Notes
Ponatinib Active Metabolite AP24567(M42) is a research reagent applied in pharmaceuticals and cancer treatment. Ponatinib Active Metabolite AP24567(M42) is an analog of Ponatinib (P688250) which is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib (P688250) is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor It is a COVID19-related research product.
Product Applications & Regulatory Search Terms
Useful product, supplier and regulatory search terms for this reference standard.