Home Stable Isotopes CS-T-98866

(+/-)-cis-anti-N2-BPDE-dG-15N5

Stable Isotopes CAT No. CS-T-98866
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(+/-)-cis-anti-N2-BPDE-dG-15N5

Stable Isotopes
Stock Status: Enquire
Live
For Research & Analytical Purposes. Not for Personal use.
Category Stable Isotopes
API Family --
Storage Refer MSDS for complete information.
Hazard Information Refer MSDS for complete information.

(+/-)-cis-anti-N2-BPDE-dG-15N5 Product Information

(+/-)-cis-anti-N2-BPDE-dG-15N5 is listed under Stable Isotopes. It is associated with and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-98866.

Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.

Technical Data

Product Name
(+/-)-cis-anti-N2-BPDE-dG-15N5
CAS No.
-
CAT No.
CS-T-98866
Molecular Formula
C30H29ยน5N5O7
Molecular Weight
576.55
Category
Storage Condition
Refer MSDS for complete information.
IUPAC Name
(+/-)-cis-anti-N2-BPDE-dG-15N5
Hazard Compound
Refer MSDS for complete information.

Description

Overview
"(+/-)-cis-anti-N2-BPDE-dG-15N5 is an isotope labelled analog of (-)-trans-anti-N2-BPDE-dG (B676630), which is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair."
Synonyms
"[7S-(7a,8รŸ,9รŸ,10รŸ)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-15N5; Benzo[a]pyrene Guanosine deriv.-15N5; (+/-)-cis-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene-15N5"
Application Notes
"(+/-)-cis-anti-N2-BPDE-dG-15N5 is an isotope labelled analog of (-)-trans-anti-N2-BPDE-dG (B676630), which is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair."
References
"Skosareva, L. et al.: DNA Repair., 11, 367 (2012); Minero, A. et al.: FEBS J. et al.: 279, 3965 (2012); Hoare, S. et al.: Biochem., 39, 12252 (2000); Subach, O. et al.: Biochem., 45, 6142 (2006);"
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