Product Detail
(+)-trans-anti-BPDE-N2-dG-d8
Stable Isotopes
Stock Status: Enquire
Live
For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
--
Storage
Refer MSDS for complete information.
Hazard Information
Refer MSDS for complete information.
(+)-trans-anti-BPDE-N2-dG-d8 Product Information
(+)-trans-anti-BPDE-N2-dG-d8 is listed under Stable Isotopes. It is associated with and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-98865.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
(+)-trans-anti-BPDE-N2-dG-d8
CAS No.
-
CAT No.
CS-T-98865
Molecular Formula
C30H19D8N5O7
Molecular Weight
577.61
Category
Storage Condition
Refer MSDS for complete information.
IUPAC Name
(+)-trans-anti-BPDE-N2-dG-d8
Hazard Compound
Refer MSDS for complete information.
Description
Overview
"Isotope labelled (+)-trans-anti-BPDE-N2-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Also, as a common concern due to tobacco smoke, this compound used to obtain a better understanding of the effects of carcinnogen-DNA adducts."
Synonyms
"(+)-trans-anti-Benzo[a]pyrene-dG-d8; 10S(+)-trans-anti-[Py]-N2-dG-d8; [7R-(7a,8ß,9ß,10a)]-2'-deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-d8; Benzo[a]pyrene guanosine deriv.-d8; (+)-r-7,t-8-Dihydroxy-t-9,10-oxy-7,8,9,10-tetra"
Application Notes
"Isotope labelled (+)-trans-anti-BPDE-N2-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Also, as a common concern due to tobacco smoke, this compound used to obtain a better understanding of the effects of carcinnogen-DNA adducts."
References
"Skosareva, L. et al.: DNA Repair., 11, 367 (2012); Minero, A. et al.: FEBS J. et al.: 279, 3965 (2012); Strasser, A. et al.: Cancer Epidemiol. Biomark. Prev., 22, 382 (2013);"
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