Abrocitinib is a medication used to treat moderate-to-severe atopic dermatitis in adults. However, during its production, impurities can be formed that can affect its purity and efficacy. These impurities can include unknown or unidentified substances, as well as known impurities that are above the acceptable limit. Therefore, it is important to monitor and control the impurities present in Abrocitinib to ensure its safety and effectiveness for patients.