Barnidipine is a calcium channel blocker used for the treatment of hypertension. However, like all pharmaceuticals, it may contain impurities that can affect its potency and safety. These impurities can be formed during the manufacturing process or storage of the drug. Thus, it is essential to identify and monitor the impurities present in barnidipine to ensure its quality and efficacy. This can be done through various analytical techniques such as HPLC, LC-MS, and NMR spectroscopy.