Butamirate is a medication used to treat coughs and respiratory illnesses. However, during the manufacturing process of this drug, impurities can be introduced into the final product. These impurities can be harmful and pose a risk to human health. Therefore, it is important to closely monitor the production of Butamirate and ensure that the impurities are kept to a minimum. Various analytical techniques such as HPLC and GC are utilized for the detection and quantification of these impurities.