Cefpirome is a fourth-generation cephalosporin antibiotic used to treat severe bacterial infections. However, during the manufacturing process, impurities can be introduced or formed, which can affect the purity, safety, and efficacy of the drug. Cefpirome impurities may include related substances, degradation products, or residual solvents. It is critical to identify and characterize these impurities to ensure the quality and safety of the drug product.