Ceftizoxime is a third-generation cephalosporin antibiotic used to treat various bacterial infections. However, it may contain certain impurities which can affect its efficacy and safety. These impurities can be either process-related or degradation products. The identification and characterization of these impurities are critical for ensuring the quality, safety, and efficacy of the drug product. Analytical methods such as chromatography and spectroscopy are commonly used to detect and quantify these impurities.