Ceftriaxone is an antibiotic used to treat a wide range of bacterial infections. However, during the manufacturing process, impurities may be introduced that can affect the drug's purity, potency, and safety. These impurities can include related compounds, degradation products, and residual solvents. It is important to identify and control these impurities to ensure the quality of the drug product. Various analytical techniques are used to detect and quantify these impurities, including HPLC, GC, and LC-MS.